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  1. Mindful breathing for cancer pain: efficacy of a single 20-minute session - a randomised controlled study
    Tan SB, Chai CS, Ng DLC, Zainuddin SI, Capelle DP, Lam CL, et al.
    BMJ Support Palliat Care, 2024 Aug 20.
    PMID: 39164043 DOI: 10.1136/spcare-2023-004762
    OBJECTIVES: Cancer pain is a prevalent and challenging symptom affecting a significant number of patients globally, with inadequate control remaining a substantial challenge despite advancements in pain management. Non-pharmacological interventions, including mindfulness-based approaches, have shown promise in alleviating cancer-related pain. This study aimed to explore the efficacy of a single session of 20-minute mindful breathing in reducing pain among patients with cancer.

    METHODS: A randomised controlled study was conducted at the University of Malaya Medical Centre, Malaysia, involving adult cancer inpatients with a pain score of ≥4/10. Participants were randomly assigned to a 20-minute mindful breathing intervention or a 20-minute supportive listening control group. Outcome measures included pain intensity, pain unpleasantness and Hospital Anxiety and Depression Scale score, assessed before and after the intervention.

    RESULTS: The 20-minute mindful breathing sessions demonstrated significant efficacy in reducing pain intensity, pain unpleasantness and anxiety compared with the control group.

    CONCLUSION: This research broadens the repertoire of cancer pain management by highlighting the rapid and holistic benefits of a single session of 20-minute mindful breathing. The findings suggest the potential integration of brief mindfulness exercises into routine cancer care to enhance pain management and overall well-being.

  2. Prevalence of Culture-Confirmed Pulmonary Tuberculosis Requiring ICU Admission and the Trend in Prevalence Before and During the COVID-19 Pandemic in a Tertiary Academic Medical Center in Kuala Lumpur, Malaysia: A 7-Year Retrospective Cohort Study
    Atiya N, Hasan MS, Wong CK, Abdullah A, Lau KS, Cheah EG, et al.
    Asia Pac J Public Health, 2025 Feb 28.
    PMID: 40017331 DOI: 10.1177/10105395251319923
    There are limited data on pulmonary tuberculosis (PTB) requiring intensive care unit (ICU) admission despite its high mortality rate. The objectives of our study were to determine the prevalence of culture-confirmed PTB requiring ICU admission and the trend in prevalence before and during the COVID-19 pandemic. A retrospective cohort study was conducted on all patients aged ≥18 years with culture-confirmed PTB requiring ICU admission in a Malaysian tertiary academic medical center from 2015 to 2021. The linear-by-linear association test was performed to determine if the trend in prevalence was significant. The overall prevalence of culture-confirmed PTB requiring ICU admission was 8.0% (139/1736). Between 2015 and 2021, the prevalence increased by 5.8% from 1.6% (5/312) to 7.4% (16/215) (P < .001). This study demonstrated an overall low but increasing trend in the prevalence of culture-confirmed PTB requiring ICU admission. Disruption in TB services during the COVID-19 pandemic may have impacted the prevalence trend.
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