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The impact of a computerised dairy information system on large dairy farms in Malaysia

Pharo HJ, Sopian MJ

Acta Vet Scand Suppl, 1988;84:197-9.
PMID: 3232607
Chromosomes of gaur cross domestic cattle hybrids

Bongso TA, Hilmi M, Sopian M, Zulkifli S

Res Vet Sci, 1988 Mar;44(2):251-4.
PMID: 3387680

The chromosomes of five gaur (Bos gaurus hubbacki) domestic cattle (B indicus cross B taurus) hybrids (three females, two males) were studied using the leucocyte culture method and centromeric (C) banding technique. All the hybrids had a diploid chromosome number of 2n = 58, made up of two submetacentric autosomes (different in size) and 54 acrocentric autosomes, most of which could be arranged in pairs in descending order of size. The sex (X) chromosomes in females were a pair of submetacentric chromosomes smaller than the submetacentric autosomes. The Y chromosome in males was a small submetacentric chromosome. The C banding patterns were useful in identifying the X and Y chromosomes and the inherited submetacentric autosomes from the gaur sire. Phenotypically, the hybrids resembled normal B indicus cross B taurus calves except for the presence of a distinct hump-like dorsal ridge containing the spinous processes of the third to 11th thoracic vertebrae, upright 'deer-like' ears and long lean legs. The potential of these hybrids as important genetic resources for meat production is stressed.
Fulltext The role of lycopene for the amelioration of glycaemic status and peripheral antioxidant capacity among the Type II diabetes mellitus patients: a case-control study

Leh HE, Mohd Sopian M, Abu Bakar MH, Lee LK

Ann Med, 2021 12;53(1):1059-1065.
PMID: 34180336 DOI: 10.1080/07853890.2021.1943515

BACKGROUND: The use of lycopene as a complementary medicine for Type II diabetes mellitus (T2DM) is limited and controversial. This study evaluated the effect of lycopene intake on the changes of glycaemic status and antioxidant capacity among the T2DM patients.
PATIENTS AND METHODS: This case-control study involved the participation of 87 patients and 122 healthy individuals. Lycopene intake was assessed by using a food frequency questionnaire. The peripheral antioxidant capacity among the T2DM patients was evaluated. Glycated haemoglobin (HbA1c) and fasting plasma glucose (FPG) were measured as indications of glycaemic status.
RESULTS: Peripheral antioxidant capacity was significantly lower in the T2DM group. Direct positive correlations were found between the lycopene intake and peripheral antioxidant level among the T2DM patients. Contrarily, HbA1c and FPG levels decreased significantly with the higher lycopene intake.
CONCLUSIONS: T2DM patients with a higher lycopene intake showed a greater peripheral antioxidant capacity and better glycaemic control. Lycopene may act to ameliorate oxidative stress and improve the pathophysiology of T2DM.
Fulltext Efficacy of multigrain supplementation in type 2 diabetes mellitus: A pilot study protocol for a randomized intervention trial

Mohd Ariffin NA, Mohd Sopian M, Lee LK

World J Diabetes, 2023 May 15;14(5):606-616.
PMID: 37273251 DOI: 10.4239/wjd.v14.i5.606

BACKGROUND: Uncontrolled type 2 diabetes mellitus (T2DM) may lead to microvascular complications (nephropathy, retinopathy, and neuropathy) and cardiovascular diseases. The beta-glucan content in grains has the potential to improve insulin sensitivity, lowering postprandial glucose response and reducing inflammation degrees. A proper combination of grains not only satisfies human body's need, but also provides essential and reasonable nutritional contents. However, no trial has been conducted to evaluate the roles of multigrain in T2DM.
AIM: To determine the efficacy of multigrain supplementation among T2DM patients.
METHODS: From October 2020 to June 2021, a total of 50 adults living with T2DM, who were receiving standard diabetes care at Day Care Clinic, were randomized into either a supplementation group or a control group. The supplementation group received twice daily 30 g multigrain supplement (equivalent to 3.4 g beta-glucan) with standard medication for 12 wk, while the control group was prescribed with standard medication. Parameters such as glycemic control (HbA1c, FPG, and HOMO-IR), cardiometabolic profile (lipid profile, renal function test, and liver function test), oxidative stress status, nutritional status, and quality of life (QoL) were assessed at two time points: Baseline and the end of the treatment period (week 12).
RESULTS: The primary outcomes were the mean difference of glycated haemoglobin (%), fasting plasma glucose, and serum insulin as intervention effects. Secondary outcomes included the measurement of cardiometabolic profile, antioxidative and oxidative stress status, nutritional status indices, and QoL. Tertiary outcomes involved the determination of safety and tolerability, and supplementation compliance.
CONCLUSION: The present clinical trial will reveal the effectiveness of multigrain supplementation among T2DM patients for the improvement of diabetes management.
Progress in the use of computerised recording systems in dairy cow monitoring and extension in Malaysia

Pharo HJ, Sopian MJ, Kamaruddin M, Abu Hassan MA, Cheah PF, Choo TW

Trop Anim Health Prod, 1990 May;22(2):77-88.
PMID: 2371756

The emphasis on cow records in Malaysian dairy extension programmes reflects the importance of herd fertility in the economics of dairying. Manual record keeping has not been able to make an impact on management due to difficulties experienced in quality control of the data and in analysing the data to produce useful information for farm managers. Computerised recording systems have been in use in Malaysia since 1985, both on government farms and in the small-holder dairy sector. The aim of both systems is firstly to improve farm efficiency by the provision of information to managers and extension workers and secondly to provide information for departmental planning purposes. The systems used in Malaysia are outlined, and the results over the first three years of operation are summarised.
Knowledge, Decision-Making and Acceptance of Human Papilloma Virus Vaccination among Parents of Primary School Students in Kota Bharu, Kelantan, Malaysia

Mohd Sopian M, Shaaban J, Mohd Yusoff SS, Wan Mohamad WMZ

Asian Pac J Cancer Prev, 2018 Jun 25;19(6):1509-1514.
PMID: 29936724

Background: The incidence of cervical cancer in younger women remains high. This is worrisome as it affects
future generations. Therefore Malaysia implements human papilloma virus (HPV) vaccination as a national vaccination
program. Parents play an important role in determining the success of this HPV vaccination program among schoolaged
girls by their compliance. Objective: To assess parental knowledge, decision-making and acceptance of HPV
vaccination. Methods: This cross sectional study was conducted among 280 randomly selected parents of primary
school students aged 11 in Kota Bharu using a pre-validated self-administered questionnaire to assess knowledge and
decision-making with regard to HPV vaccination. Results: Most parents (62%) were shown to have poor knowledge
while most decision-making was shared. Age of respondents (adjusted odds ratio ‘AOR’= 1.09; 95% confidence interval
‘CI’= 1.04-1.14; p <0.001) and good knowledge of HPV vaccination (AOR= 16.32; 95% CI= 7.32-36.4; p <0.001) were
significantly associated with HPV vaccine acceptance. Conclusion: The majority of parents exhibited poor knowledge
which may affect their decision-making and uptake of HPV vaccination among their children. This highlights the need
to better educate parents on HPV vaccination.