Primary sinonasal Non-Hodgkin’s Lymphoma’s
(NHLs) are quite rare and emulate the presentation
of benign inflammatory diseases. It is challenging to
distinguish them morphologically and radiologically
from other malignant neoplasms.
We report a 37-year-old male patient who presented
with obstruction of the nasal passages, rhinorrhoea,
epistaxis, post nasal drip, facial swelling, orbital
symptoms and pyrexia. The mass was a nasal diffuse large
B-cell lymphoma confirmed by immunohistochemistry.
After the first cycle of chemotherapy was started, the
patient improved with resolution of the facial swelling,
pain and visual defects.
A high index of suspicion is required to differentiate
sinonasal lymphomas from other lesions.