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  1. Outer hair cell functioning in infants with iron deficiency anemia
    Sundagumaran H, Seethapathy J
    Int J Pediatr Otorhinolaryngol, 2020 Nov;138:110393.
    PMID: 33152983 DOI: 10.1016/j.ijporl.2020.110393
    BACKGROUND: Distortion product otoacoustic emissions (DPOAE) in infants with Iron Deficiency Anemia (IDA) helps in understanding the cochlear status especially the functioning of outer hair cells.

    OBJECTIVES: To analyze the presence of DPOAE across frequencies and DP amplitude in infants with and without IDA.

    METHOD: DPOAE were recorded on 40 infants with IDA and 40 infants without IDA in the age range of 6-24 months. Cubic DPOAEs (2f1-f2) were measured at six f2 frequencies (1500 Hz, 2000 Hz, 3000 Hz, 4500 Hz, 6000 Hz & 8000 Hz) with primary tone stimulus of intensity L1 equal to 65 dBSPL and L2 equal to 55 dBSPL. Immittance audiometry was performed using 226 Hz probe tone prior to DPOAE recording to ascertain normal middle ear functioning.

    RESULTS: DPOAEs were present in all infants with and without IDA across frequencies tested. DP amplitude across the frequencies did not show any statistically significant difference (p outer hair cell functioning as there were no changes observed in the DPOAE amplitude levels between infants with IDA and infants without IDA. Iron status does not seem to have a direct effect on outer hair cell functioning in infants. However, fine structure DPOAEs can reveal even more precise changes (if any) that are caused due to iron deficiency.

    Matched MeSH terms: Hair Cells, Auditory, Outer*
  2. The development of a fast method for recording Schroeder-phase masking functions
    Rahmat S, O'Beirne GA
    Hear Res, 2015 Dec;330(Pt A):125-33.
    PMID: 26209881 DOI: 10.1016/j.heares.2015.07.013
    Schroeder-phase masking complexes have been used in many psychophysical experiments to examine the phase curvature of cochlear filtering at characteristic frequencies, and other aspects of cochlear nonlinearity. In a normal nonlinear cochlea, changing the "scalar factor" of the Schroeder-phase masker from -1 through 0 to +1 results in a marked difference in the measured masked thresholds, whereas this difference is reduced in ears with damaged outer hair cells. Despite the valuable information it may give, one disadvantage of the Schroeder-phase masking procedure is the length of the test - using the conventional three-alternative forced-choice technique to measure a masking function takes around 45 min for one combination of probe frequency and intensity. As an alternative, we have developed a fast method of recording these functions which uses a Békésy tracking procedure. Testing at 500 Hz in normal hearing participants, we demonstrate that our fast method: i) shows good agreement with the conventional method; ii) shows high test-retest reliability; and iii) shortens the testing time to 8 min.
    Matched MeSH terms: Hair Cells, Auditory, Outer/physiology*
  3. Relation of distortion product otoacoustic emission with tinnitus
    Ami M, Abdullah A, Awang MA, Liyab B, Saim L
    Laryngoscope, 2008 Apr;118(4):712-7.
    PMID: 18176342 DOI: 10.1097/MLG.0b013e318161e521
    To investigate cochlear outer hair cell function based on distortion product otoacoustic emission (DPOAE) in patients with tinnitus.
    Matched MeSH terms: Hair Cells, Auditory, Outer/physiology*
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