MyMedR

Chaubal TV, Bapat R, Poonja K

Am J Med, 2017 10;130(10):e451.

PMID: 28528920 DOI: 10.1016/j.amjmed.2017.04.026

Matched MeSH terms: Mandible/abnormalities*

Evaluation of mentum deformities of Chironomus spp. (Chironomidae: Diptera) larvae using modified toxic score index (MTSI) to assess the environmental stress in Juru River Basin, Penang, Malaysia

Al-Shami SA, Salmah MR, Hassan AA, Azizah MN

Environ Monit Assess, 2011 Jun;177(1-4):233-44.

PMID: 20697808 DOI: 10.1007/s10661-010-1630-1

Morphological mentum deformities which represent sublethal effect of exposure to different types of pollutants were evaluated in Chironomus spp. larvae inhabiting three polluted rivers of Juru River Basin in northwestern peninsular Malaysia. Using mentum deformity incidences, the modified toxic score index (MTSI) was developed based on Lenat's toxic score index (TSI). The suggested MTSI was compared with TSI in terms of its effectiveness to identify different pollutants including heavy metals. The MTSI showed stronger relationship to total deformity incidence expressed as percentage. Additionally, the multivariate RDA model showed higher capability of MTSI to explain the variations in heavy metal contents of the river sediments. The MTSI was recommended in bioassessment of water and sediment quality using the mentum deformities of Chironomus spp. larvae from aquatic ecosystems receiving anthropogenic, agricultural, or industrial discharges.

Matched MeSH terms: Mandible/abnormalities*

Hypoglossia congenita with anterior maxillo-mandibular fusion

Arshad AR, Goh CS

Br J Plast Surg, 1994 Mar;47(2):139-41.

PMID: 8149059

Two cases of hypoglossia congenita with anterior maxillo-mandibular fusion are reported. One is a case of hypoglossia with anterior maxillo-mandibular fusion and the other is a case of hypoglossia-hypodactylia with anterior maxillo-mandibular fusion. This condition presents the anaesthetist with the problem of airway management during the surgery. A simple technique using a nasopharyngeal tube was used for these two cases, with satisfactory results.

Matched MeSH terms: Mandible/abnormalities*

Duplication of lower lip and mandible--a rare diprosopus

Suhaili DN, Somasundaram S, Lau SH, Ajura AJ, Roslan AR, Ramli R

Int J Pediatr Otorhinolaryngol, 2011 Jan;75(1):131-3.

PMID: 21067822 DOI: 10.1016/j.ijporl.2010.10.004

Diprosopus or duplication of the lower lip and mandible is a very rare congenital anomaly. We report this unusual case occurring in a girl who presented to our hospital at the age of 4 months. Surgery and problems related to this anomaly are discussed.

Matched MeSH terms: Mandible/abnormalities*

Feeding and reflux in children after mandibular distraction osteogenesis for micrognathia: A systematic review

Breik O, Umapathysivam K, Tivey D, Anderson P

Int J Pediatr Otorhinolaryngol, 2016 Jun;85:128-35.

PMID: 27240511 DOI: 10.1016/j.ijporl.2016.03.033

Mandibular distraction osteogenesis (MDO) is becoming increasingly more commonly used as in neonates and infants with upper airway obstruction secondary to micrognathia. A significant number of these children are dependent on nasoenteric feeding or gastrostomies after birth for adequate nutrition and often suffer from gastro-esophageal reflux (GERD).

OBJECTIVE: This analysis is a subset of a larger systematic review. The objective of this study is to determine the effects of MDO on feeding and GERD.

DATA SOURCES: The databases searched included PubMed, Embase, Scopus, Web of Knowledge and grey literature sources.

STUDY SELECTION: The inclusion criterion included studies in children with clinical evidence of micrognathia/Pierre Robin Sequence (PRS) who have failed conservative treatments, including both syndromic (sMicro) and non-syndromic (iPRS) patients. 21 studies relevant to feeding and 4 studies relevant to GERD outcomes were included. All studies included were case series and case reports.

RESULTS: MDO leads to a significant improvement in feeding, with 82% of children feeding exclusively orally after surgery. The overall percentage of children with iPRS who were feeding orally was 93.7% compared with only 72.9% in the sMicro group (p<0.004). A growth decline within the first six weeks after surgery was observed in multiple studies. Overall, out of 70 patients with pre-operative GERD, only four had evidence of GERD after surgery.

CONCLUSIONS: Considering the limitations of this systematic review, this study found that successful relief of airway obstruction by MDO leads to improvement of feeding and improvement in symptoms of GERD in children with upper airway obstruction secondary to micrognathia. Clinicians need to be aware of the risk of growth decline in the initial post-operative period.

Matched MeSH terms: Mandible/abnormalities

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