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  1. Okekpa SI, S. M. N. Mydin RB, Ganeson S, Gopalan S, Musa MY
    Asian Pac J Cancer Prev, 2020 08 01;21(8):2183-2187.
    PMID: 32856842 DOI: 10.31557/APJCP.2020.21.8.2183
    Heated debates have been on-going about tea consumption and the incidence of cancer, especially in head and
    neck cancer types. This study aimed to review the association between tea consumption habits and nasopharyngeal
    cancer (NPC). Methods: This review was carried out in accordance with the PRISMA-P protocol. Literature search
    for journal articles that published studies on the relationship between tea consumption and NPC was performed via
    databases, such as Elsevier, PubMed, Science Direct, Springer Link, Google, and Google Scholar, for 10 years from
    2008 to 2018. Relevant studies were obtained by applying the pre-determined keywords, such as nasopharyngeal cancer,
    tea consumption and NPC, risk factors of NPC and benefits of tea consumption. Results: A total of 126 articles was
    retrieved. These articles were subjected to eligibility assessment. Six articles remained after applying the inclusion
    criteria. Results suggest that habitual tea consumption reduces NPC. Tea consumption significantly reduces NPC with
    all the studies having a p-value ≤0.05. Meta-analysis showed statistical association between tea consumption and NPC
    risk with OR=0.865 at 95% CI (0.806-0.929). Conclusion: This study suggests that habitual tea consumption could
    be associated with prevention of NPC development. Additional studies are needed to further understand the molecular
    role of bioactive compound and potential health benefit of tea consumption in NPC prevention.
    Matched MeSH terms: Nasopharyngeal Neoplasms/prevention & control*
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