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  1. Fulltext A multinational phase IIb/III trial of beraprost sodium, an orally active prostacyclin analogue, in patients with primary glomerular disease or nephrosclerosis (CASSIOPEIR trial), rationale and study design
    Nakamoto H, Fujita T, Origasa H, Isono M, Kurumatani H, Okada K, et al.
    BMC Nephrol, 2014;15:153.
    PMID: 25233856 DOI: 10.1186/1471-2369-15-153
    Chronic kidney disease (CKD) is public health concern even in Asian countries. TRK-100STP, a sustained release tablet of an orally-active prostacyclin analogue, beraprost sodium, is suggested to suppress worsening of some parameters of renal filtration function, containing in slope of 1/serum creatinine (1/SCr) vs. time in a phase II clinical trial.
    Matched MeSH terms: Nephrosclerosis/drug therapy*
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