Affiliations 

  • 1 CQM - Centro de Química da Madeira, MMRG, Universidade da Madeira, Campus da Penteada, 9020-105 Funchal, Portugal. jaison.jeevanandam@staff.uma.pt
  • 2 Curtin Malaysia Research Institute, Curtin University Malaysia, CDT 250, 98009 Miri Sarawak, Malaysia
  • 3 Rowan University, Henry M. Rowan College of Engineering, Department of Chemical Engineering, 201 Mullica Hill Rd, Glassboro, NJ 08028, USA
  • 4 Department of Chemical Engineering, Curtin University Malaysia, CDT 250, 98009 Miri Sarawak, Malaysia
  • 5 Nanostruc, Research Group, Chemistry Department, Faculty of Science, Helwan University, Helwan 11795, Egypt
  • 6 Chemical Engineering Department, University of Tennessee, Chattanooga, 615 McCallie Ave, Chattanooga, TN 37403, USA
Nanoscale, 2022 Feb 17;14(7):2534-2571.
PMID: 35133391 DOI: 10.1039/d1nr08144f

Abstract

Green synthesis approaches are gaining significance as promising routes for the sustainable preparation of nanoparticles, offering reduced toxicity towards living organisms and the environment. Nanomaterials produced by green synthesis approaches can offer additional benefits, including reduced energy inputs and lower production costs than traditional synthesis, which bodes well for commercial-scale production. The biomolecules and phytochemicals extracted from microbes and plants, respectively, are active compounds that function as reducing and stabilizing agents for the green synthesis of nanoparticles. Microorganisms, such as bacteria, yeasts, fungi, and algae, have been used in nanomaterials' biological synthesis for some time. Furthermore, the use of plants or plant extracts for metal and metal-based hybrid nanoparticle synthesis represents a novel green synthesis approach that has attracted significant research interest. This review discusses various biosynthesis approaches via microbes and plants for the green preparation of metal and metal oxide nanoparticles and provides insights into the molecular aspects of the synthesis mechanisms and biomedical applications. The use of agriculture waste as a potential bioresource for nanoparticle synthesis and biomedical applications of biosynthesized nanoparticles is also discussed.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.