Affiliations 

  • 1 School of Pharmacy, International Medical University, Kuala Lumpur, Malaysia; School of Pharmacy, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia. Electronic address: chiasiangkow@imu.edu.my
  • 2 School of Pharmacy, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia
  • 3 School of Applied Sciences, University of Huddersfield, Huddersfield, United Kingdom; School of Biomedical Sciences & Pharmacy, University of Newcastle, Callaghan, Australia
Mol Immunol, 2022 May;145:78-79.
PMID: 35303531 DOI: 10.1016/j.molimm.2022.03.001

Abstract

We read with interest the narrative review authored by Kiser et al. (2021), which discussed extensively the antioxidant effect and anti-inflammatory effect of sulforaphane, a dietary supplement found in high amounts in cruciferous vegetables that ais orally accessible and well-tolerated. Notably, in their review, the authors also discussed the potential use of sulforaphane in patients with coronavirus disease 2019 (COVID-19). Sulforaphane mediates the inhibitory effect on NLRP3 inflammasome activation and we believe that this could be the main mechanism where sulforaphane is useful for patients with COVID-19.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.