Affiliations 

  • 1 Department of Medicine, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia
  • 2 Department of Community Health, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia
  • 3 Department of Radiology, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia
Neurol Clin Neurosci, 2023 Jan;11(1):17-26.
PMID: 36714457 DOI: 10.1111/ncn3.12677

Abstract

BACKGROUND: Neurological involvement associated with SARS-CoV-2 infection has been reported from different regions of the world. However, data from South East Asia are scarce. We described the neurological manifestations and their associated factors among the hospitalized COVID-19 patients from an academic tertiary hospital in Malaysia.

METHODS: A cross-sectional observational study of hospitalized COVID-19 patients was conducted. The neurological manifestations were divided into the self-reported central nervous system (CNS) symptoms, stroke associated symptoms, symptoms of encephalitis or encephalopathy and specific neurological complications. Multiple logistic regression was performed using demographic and clinical variables to determine the factors associated with outcome.

RESULTS: Of 156 hospitalized COVID-19 patients with mean age of 55.88 ± 6.11 (SD) years, 23.7% developed neurological complications, which included stroke, encephalitis and encephalopathy. Patients with neurological complications were more likely to have diabetes mellitus (p = 0.033), symptoms of stroke [limb weakness (p 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.