Affiliations 

  • 1 School of Computer Science, MIT World Peace University, Pune, India
  • 2 Model Institute of Engineering and Technology, Jammu, J&K, India
  • 3 Operations and Regulatory Affairs, Children's National Hospital, DC, USA
  • 4 Zoology Department and Research Centre, Sarah Tucker College (Autonomous), Affiliated to Manonmaniam Sundaranar University, Tirunelveli, India
  • 5 Universiti Tun Hussein Onn Malaysia (UTHM), Malaysia
  • 6 Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
  • 7 Department of Electronics and Communication Engineering, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur, Andhra Pradesh, India
Biomed Res Int, 2023;2023:6970256.
PMID: 36760472 DOI: 10.1155/2023/6970256

Abstract

The application of computational approaches in medical science for diagnosis is made possible by the development in technical advancements connected to computer and biological sciences. The current cancer diagnosis system is becoming outmoded due to the new and rapid growth in cancer cases, and new, effective, and efficient methodologies are now required. Accurate cancer-type prediction is essential for cancer diagnosis and treatment. Understanding, diagnosing, and identifying the various types of cancer can be greatly aided by knowledge of the cancer genes. The Convolution Neural Network (CNN) and neural pattern recognition (NPR) approaches are used in this study paper to detect and predict the type of cancer. Different Convolution Neural Networks (CNNs) have been proposed by various researchers up to this point. Each model concentrated on a certain set of parameters to simulate the expression of genes. We have developed a novel CNN-NPR architecture that predicts cancer type while accounting for the tissue of origin using high-dimensional gene expression inputs. The 5000-person sample of the 1-D CNN integrated with NPR is trained and tested on the gene profile, mapping with various cancer kinds. The proposed model's accuracy of 94% suggests that the suggested combination may be useful for long-term cancer diagnosis and detection. Fewer parameters are required for the suggested model to be efficiently trained before prediction.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.