From parasomnia to agrypnia excitata - An illustrative case on diagnostic approach

Fong SL 1 , Dy Closas AMF 1 , Lim TT 2 , Lean PL 3 , Loh EC 4 , Lim SY 1 Show all authors , Tan AH 5

Affiliations 

  • 1 Division of Neurology, Department of Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia
  • 2 Island Hospital, Penang, Malaysia
  • 3 Department of Medicine, Seberang Jaya Hospital, Penang, Malaysia
  • 4 Division of Palliative Medicine, Department of Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia
  • 5 Division of Neurology, Department of Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia. Electronic address: aihuey.tan@gmail.com
Parkinsonism Relat Disord, 2023 Apr;109:105332.
PMID: 36948111 DOI: 10.1016/j.parkreldis.2023.105332

Abstract

The diagnostic approach to sleep-related movements disorders is seldom discussed. We report a case of fatal familial insomnia who initially presented with persistent limb movements in sleep, which later progressed to a state of agrypnia excitata. Here, the evaluation of abnormal movements in sleep is discussed using a step-by-step diagnostic approach. Although no cure is available for fatal familial insomnia, prompt recognition of this condition is important to facilitate proper management, including the involvement of interdisciplinary neuropalliative care.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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