Affiliations 

  • 1 Department of Medicine Keningau Hospital Keningau Malaysia
  • 2 Department of Respiratory Medicine Queen Elizabeth Hospital Kota Kinabalu Malaysia
  • 3 Medical Department, Faculty of Medicine and Health Sciences Universiti Malaysia Sabah Kota Kinabalu Malaysia
  • 4 Department of Pathology Queen Elizabeth Hospital Kota Kinabalu Malaysia
Respirol Case Rep, 2023 Aug;11(8):e01197.
PMID: 37501686 DOI: 10.1002/rcr2.1197

Abstract

Pulmonary extra-nodal marginal zone B-cell lymphoma, also known as extra-nodal mucosa-associated lymphoid tissue (MALT) lymphoma, is rare among all non-Hodgkin lymphomas and generally among all pulmonary malignancies. We present a 46-year-old lady with persistent right lower lung consolidation despite earlier treatment efforts with intravenous antibiotics for community acquired pneumonia. Apart from initial presentation with a short 3-day history of fever, cough and shortness of breath, she had remained largely asymptomatic throughout the follow-up period. Flexible bronchoscopy done ruled out infectious aetiologies but transbronchial lung biopsies showed atypical lymphocytes. A computed tomography guided core biopsy of her right lung consolidation was subsequently performed, confirming a diagnosis of pulmonary MALT lymphoma. She was promptly referred to the haematology team for further management and commencement of chemotherapy. Pulmonary MALT lymphoma, albeit uncommon and often follows a relatively indolent cause, should be considered as a differential diagnosis among patients with persistent lung consolidation.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.