Affiliations 

  • 1 Division of Genetics, ICAR-Indian Agricultural Research Institute (IARI), Pusa Campus, New Delhi, Delhi, India 110012
  • 2 Department of Botany, Deshbandhu College, University of Delhi, Delhi, India 110019
  • 3 Bangalore Bioinnovation Centre, Life Sciences Park, Electronics City Phase 1, Bengaluru, Karnataka, India 560100
  • 4 Department of Botany, Deen Dayal Upadhyay College, University of Delhi, Dwarka, Delhi, India 110078
  • 5 Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt 11156
Saudi J Biol Sci, 2023 Nov;30(11):103814.
PMID: 37841664 DOI: 10.1016/j.sjbs.2023.103814

Abstract

Ascariasis and intestinal parasitic nematodes are the leading cause of mass mortality infecting many people across the globe. In light of the various deleterious side effects of modern chemical-based allopathic drugs, our preferences have currently shifted towards the use of traditional plant-based drugs or botanicals for treating diseases. The defensive propensities in the botanicals against parasites have probably evolved during their co-habitation with parasites, humans and plants in nature and hence their combative interference in one another's defensive mechanisms has occurred naturally ultimately being very effective in treating diseases. This article broadly outlines the utility of plant-based compounds or botanicals prepared from various medicinal herbs that have the potential to be developed as effective therapies against the important parasites causing ascariasis and intestinal hookworm infections leading to ascariasis & infections and thereby human mortality, wherein allopathic treatments are less effective and causes enormous side-effects.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.