Affiliations 

  • 1 Aconsultant nephrologist, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia. Electronic address: tanminhui83@yahoo.com
  • 2 Aconsultant nephrologist, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
Clin Med (Lond), 2022 Mar;22(2):169-171.
PMID: 38589183 DOI: 10.7861/clinmed.2021-0789

Abstract

Carbamazepine remains a first-line antiepileptic medication for the treatment of partial seizures. Despite its widespread use, carbamazepine has significant neurotoxicity and hypersensitivity reactions. We report a case of a patient post-kidney transplant who was on regular carbamazepine for childhood epilepsy and developed nystagmus, diplopia and a broad-base gait after receiving diltiazem. Understanding of the interaction between diltiazem and carbamazepine is necessary to prevent the neurotoxic effects.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.