3-(Adamantan-1-yl)-1-[(4-benzyl-piperazin-1-yl)meth-yl]-4-ethyl-1H-1,2,4-triazole-5(4H)-thione

Al-Abdullah ES; Al-Tuwaijri HM; El-Emam AA; Chidan Kumar CS; Fun HK

doi:10.1107/S1600536813031127

Fulltext

3-(Adamantan-1-yl)-1-[(4-benzyl-piperazin-1-yl)meth-yl]-4-ethyl-1H-1,2,4-triazole-5(4H)-thione

Al-Abdullah ES ¹ , Al-Tuwaijri HM ¹ , El-Emam AA ¹ , Chidan Kumar CS ² , Fun HK ¹

Affiliations

¹ Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, PO Box 2457, Riaydh 11451, Saudi Arabia
² X-ray Crystallography Unit, School of Physics, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia

Acta Crystallogr Sect E Struct Rep Online, 2013 Nov 23;69(Pt 12):o1813-4.

PMID: 24454243 DOI: 10.1107/S1600536813031127

Abstract

In the title compound, C26H37N5S, the piperazine ring adopts a chair conformation with the exocyclic N-C bonds in pseudo-equatorial orientations. The piperazine ring (all atoms) subtends dihedral angles of 79.47 (9) and 73.07 (9)° with the triazole and benzene rings, respectively, resulting in an approximate U-shape for the mol-ecule. No significant inter-molecular inter-actions are observed in the crystal.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.