Prosthodontic rehabilitation and management of microstomia patient presents challenges at all stages
during prosthesis fabrication; from making primary impressions to the prostheses insertion. These patients have
reduced mouth opening, and hence it can be extremely challenging to make impressions and to fabricate
dentures using the conventional methods. The present case report describes prosthodontic management of a
partially dentate patient with microstomia that developed secondary to surgical resection and radiation therapy of
head and neck cancer. A simplified novel approach has been advocated using the patient’s existing metal
removable partial denture as a key in master cast preparation.