Introduction: Korsakoff Syndrome (KS) is a preventable memory disorder
that can occur after Wernicke’s encephalopathy (WE). There is scarce
information regarding KS in Malaysia. Method: Case report. Results: A 49
year-old Chinese lady with daily alcohol use in between 15-20 units for more
than 10 years became forgetful eight months prior to her admission due to
withdrawal symptoms and a fall when she attempted to cut down her alcohol
use to 7–8 units. Examination revealed confabulation, dysdiadochokinesia,
resting and intentional tremor but not confusion, ophthalmoplegia,
nystagmus or ataxia. Mini mental state examination result was 14/30.
Investigations revealed features of chronic alcohol use and cerebral atrophy
of bilateral frontotemporal lobe. Despite aggressive treatment with
intravenous and oral thiamine, the patient’s cognitive deficit persisted. Hence
KS was diagnosed. Discussion: There is no proven treatment that can
reverse KS other than prevention. Thiamine fortification may be
implemented locally to prevent this condition.