Tumour cells behave differently than normal cells in the body. They grow and
divide in an uncontrolled manner (actively proliferating) and fail to respond to signal.
However, there are cells that become inactive and reside in quiescent phase (G0). These
cells are known as quiescence cells that are less sensitive to drug treatments (radiotherapy
and chemotherapy) than actively proliferation cells. This paper proposes a new mathe-
matical model that describes the interaction of tumour growth and immune response by
considering tumour population that is divided into three different phases namely inter-
phase, mitosis and G0. The model consists of a system of delay differential equations
where the delay, represents the time for tumour cell to reside interphase before entering
mitosis phase. Stability analysis of the equilibrium points of the system was performed
to determine the dynamics behaviour of system. Result showed that the tumour popu-
lation depends on number of tumour cells that enter active (interphase and mitosis) and
G0phases. This study is important for treatment planning since tumour cell can resist
treatment when they refuge in a quiescent state.