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A Case Series of Fetal Valproate Syndrome in the Republic of Crimea

Rybalko ON 1 , Kaladze NN 1 , Sukhareva IA 2 , Khoo CS 3

Affiliations 

  • 1 Department of Pediatrics, Physiotherapy and Health Resorts, S.I. Georgievsky Medical Academy, V.I. Vernadsky Crimean Federal University, Simferopol, Crimea, Russia
  • 2 Department of Public Health, S.I. Georgievsky Medical Academy, V.I. Vernadsky Crimean Federal University, Simferopol, Crimea, Russia
  • 3 Neurology Unit, Department of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia
J Neurosci Rural Pract, 2019 Oct;10(4):700-702.
PMID: 31831992 DOI: 10.1055/s-0039-1700599

Abstract

Valproic acid or valproate is a well-recognized potent teratogen. Antenatal exposure to this drug can cause fetal valproate syndrome (FVS), which is a constellation of distinctive dysmorphic features and congenital malformations. Despite an abundance of reports and registries about this syndrome, there is lack of information from Russia, in particular, the Republic of Crimea. We herein describe two cases of FVS from our registry.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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