The use of plants as therapy is not alien to man. Among plants that could offer novel choice to the limited therapeutic alternatives is Amaranthus caudatus. It is typically rich in bioactive compounds such as phenolic acids, lycopene, polyphenols, unsaturated fatty acids, glucosinolates, proteins, soluble peptides, flavonoids, squalene and betacarotene to say the least. As widely reported in the literature, its various capacities to fight diseases when ingested as food or medicine may not be unconnected to these bioactive compounds available in high concentrations. This current review, therefore, harmonized reports from scientific investigations that validated the use of A. caudatus for the treatment of various ailments such as Diabetes mellitus, cancer, malaria, hypercholesterolemia, atherosclerosis, helminthic and bacterial infections, inflammation, hepatic diseases and cardiovascular complications. With this, we hope to put in perspective, the key therapeutic options available in the plant.
* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.