Is malnutrition a determining factor of health-related quality of life in hemodialysis patients? A cross-sectional design examining relationships with a comprehensive assessment of nutritional status

Ng HM 1 , Khor BH 2 , Sahathevan S 3 , Sualeheen A 4 , Chinna K 1 , Gafor AHA 5 Show all authors , Goh BL 6 , Ahmad G 7 , Morad Z 8 , Daud ZAM 9 , Khosla P 10 , Karupaiah T 11 , PaTCH Study (Malaysia) Investigators

Affiliations 

  • 1 School of Medicine, Faculty of Health and Medical Sciences, Taylor's University, Subang Jaya, Selangor, Malaysia
  • 2 Faculty of Food Science and Nutrition, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia
  • 3 Department of Allied Health Sciences, Faculty of Science, Universiti Tunku Abdul Rahman, Kampar Campus, Kampar, Perak, Malaysia
  • 4 Dietetics Program, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
  • 5 Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Center, Kuala Lumpur, Malaysia
  • 6 Department of Nephrology, Serdang Hospital, Kajang, Selangor, Malaysia
  • 7 Department of Cardiology, National Heart Institute, Kuala Lumpur, Malaysia
  • 8 National Kidney Foundation of Malaysia, Petaling Jaya, Selangor, Malaysia
  • 9 Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
  • 10 Department of Nutrition and Food Science, Wayne State University, Detroit, MI, USA
  • 11 School of BioSciences, Faculty of Health and Medical Sciences, Taylor's University, Subang Jaya, Selangor, Malaysia. tilly_karu@yahoo.co.uk
Qual Life Res, 2021 Nov 08.
PMID: 34748139 DOI: 10.1007/s11136-021-03018-6

Abstract

PURPOSE: To identify relationships between health-related quality of life (HRQOL) and nutritional status in hemodialysis (HD) patients.

METHOD: Secondary data from a cross-sectional survey was utilized. HRQOL was assessed for 379 HD patients using the generic Short Form 36 (SF-36) and disease-specific Kidney-Disease Quality of Life-36 (KDQOL-36). Malnutrition was indicated by malnutrition inflammation score (MIS) ≥ 5, and presence of protein-energy wasting (PEW). The individual nutritional parameters included the domains of physical status, serum biomarkers, and dietary intake. Multivariate associations were assessed using the general linear model.

RESULTS: MIS ≥ 5 was negatively associated with SF-36 scores of physical functioning (MIS 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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