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  1. Appannah G, Pot GK, Huang RC, Oddy WH, Beilin LJ, Mori TA, et al.
    Nutr Metab Cardiovasc Dis, 2015 Jul;25(7):643-50.
    PMID: 26026208 DOI: 10.1016/j.numecd.2015.04.007
    BACKGROUND AND AIMS: Energy dense, high fat, low fibre diets may contribute to obesity in young people, however their relationships with other cardiometabolic risk factors are unclear. We examined associations between an 'energy-dense, high-fat and low-fibre' dietary pattern (DP) and cardiometabolic risk factors, and the tracking of this DP in adolescence.

    METHODS AND RESULTS: Data was sourced from participants in the Western Australian Pregnancy (Raine) Cohort Study. At 14 and 17 y, dietary intake, anthropometric and biochemical data were measured and z-scores for an 'energy dense, high fat and low fibre' DP were estimated using reduced rank regression (RRR). Associations between DP z-scores and cardiometabolic risk factors were examined using regression models. Tracking of DP z-scores was assessed using Pearson's correlation coefficient. A 1 SD unit increase in DP z-score between 14 and 17 y was associated with a 20% greater odds of high metabolic risk (95% CI: 1.01, 1.41) and a 0.04 mmol/L higher fasting glucose in boys (95% CI: 0.01, 0.08); a 28% greater odds of a high-waist circumference (95% CI: 1.00, 1.63) in girls. An increase of 3% and 4% was observed for insulin and HOMA (95% CI: 1%, 7%), respectively, in boys and girls, for every 1 SD increase in DP z-score and independently of BMI. The DP showed moderate tracking between 14 and 17 y of age (r = 0.51 for boys, r = 0.45 for girls).

    CONCLUSION: An 'energy dense, high fat, low fibre' DP is positively associated with cardiometabolic risk factors and tends to persist throughout adolescence.

  2. Fung WP, Mahoney D, Beilin LJ
    Med J Malaysia, 1984 Jun;39(2):131-4.
    PMID: 6513851
    The effects of ethanol on gastric thromboxane B2 was studied in man. A single dose of 20 ml 15% ethanol significantly inhibited the gastric secretion of thromboxane B2 whereas 20 mls of 5% ethanol were without effect. It was concluded that ethanol can suppress gastric secretion of thromboxane B2 psychosis.
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