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  1. Fulltext A technique utilising cobalt-chromium framework as a key in master cast preparation for removable prosthesis in microstomia patients: A case report
    Buzayan, Muaiyed Mahmoud, Omar Tawfiq, Choudhary, Suchismita, Sivakumara, Indumathi, Norsiah Yunus, Elkezza, Aeman
    Archives of Orofacial Sciences, 2017;12(2):110-113.
    MyJurnal
    Prosthodontic rehabilitation and management of microstomia patient presents challenges at all stages
    during prosthesis fabrication; from making primary impressions to the prostheses insertion. These patients have
    reduced mouth opening, and hence it can be extremely challenging to make impressions and to fabricate
    dentures using the conventional methods. The present case report describes prosthodontic management of a
    partially dentate patient with microstomia that developed secondary to surgical resection and radiation therapy of
    head and neck cancer. A simplified novel approach has been advocated using the patient’s existing metal
    removable partial denture as a key in master cast preparation.
  2. Does HIV infection affect the survival of dental implants? A systematic review and meta-analysis
    Sivakumar I, Arunachalam S, Choudhary S, Buzayan MM
    J Prosthet Dent, 2021 Jun;125(6):862-869.
    PMID: 32694022 DOI: 10.1016/j.prosdent.2020.04.001
    STATEMENT OF PROBLEM: Immunosuppression and coinfections associated with human immunodeficiency virus (HIV) infection pose a relative contraindication for dental implant therapy. However, although implants have been placed in patients with HIV with reasonable success, how HIV infection affects their survival is unclear.

    PURPOSE: The purpose of this systematic review of the literature and meta-analysis was to analyze the data on the survival of dental implants in patients with HIV.

    MATERIAL AND METHODS: A search for relevant articles published up to November 2019 was performed in PubMed/Medline and Cochrane databases, Clinicaltrials.gov, and Google Scholar. Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were adopted for the conduct of the systematic review. The most pertinent data were extracted and pooled for qualitative and quantitative analyses with 95% confidence intervals. Heterogeneity was analyzed by using I-squared statistics.

    RESULTS: A total of 8 studies involving 411 individuals with HIV and 1109 implants were included in the meta-analysis. The mean follow-up period was 2.8 years. A pooled estimate of 95% of implant survival rate with 95% confidence interval(92% to 96%) was noted. Heterogeneity across the 8 studies was found to be 41% with moderate true variability.

    CONCLUSIONS: This systematic review demonstrated that HIV infection does not pose a serious threat to implant survival on short-term evaluation, but the evidence is of low quality.

  3. Do Highly Active Antiretroviral Therapy Drugs in the Management of HIV Patients Influence Success of Dental Implants?
    Sivakumar I, Arunachalam S, Choudhary S, Mahmoud-Buzayan M, Tawfiq O, Sharan J
    AIDS Rev, 2020;22(1):3-8.
    PMID: 32167505 DOI: 10.24875/AIDSRev.20000107
    HIV infection is a global pandemic that affects CD4 cells in the immune system and leads to lethal opportunistic infections. The advent of highly active antiretroviral therapy (HAART) has induced a marked reduction in the viral load and an increase in the CD4 cell count, thereby changing the course of the disease from an acute life-threatening condition to chronic disease. Accordingly, need and demand for oral rehabilitation in HIV positive population have increased in recent years. However, few drugs used in the HAART regimen have also known to be associated with osteopenia and osteoporosis. Although HAART reduces the morbidity in HIV patients, it remains unknown to what extent the therapy influences the implant healing. Few scientific literatures have identified osteoporosis and HIV infection as an unconducive milieu for dental implant placement and survival but demonstrated favorable outcomes in short-term assessments. The long-term impact of bone metabolic effects of HAART on implant success remains a conundrum.
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