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SLC22A1-ABCB1 haplotype profiles predict imatinib pharmacokinetics in Asian patients with chronic myeloid leukemia
Singh O, Chan JY, Lin K,
Heng CC
, Chowbay B
PLoS One
, 2012;7(12):e51771.
PMID: 23272163
DOI:
10.1371/journal.pone.0051771
Abstract
This study aimed to explore the influence of SLC22A1, PXR, ABCG2, ABCB1 and CYP3A5 3 genetic polymorphisms on imatinib mesylate (IM) pharmacokinetics in Asian patients with chronic myeloid leukemia (CML).
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