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Fulltext Opinions of the Urban Women on Pap test: Evidence from Bangladesh

Mustari S, Hossain B, Diah NM, Kar S

Asian Pac J Cancer Prev, 2019 06 01;20(6):1613-1620.
PMID: 31244279 DOI: 10.31557/APJCP.2019.20.6.1613

Each year, many countries from developed world publishes reports on early cancer detection; which is absolutely
absent in most developing countries like Bangladesh.Very limited evidence is found on the role and acceptance of Pap
test among the women of Bangladesh in determining cervical cancer. More research and updates are needed relating Pap
test in early detection of cervical cancer. Thus the purpose of this study is set to assess the opinions of Bangladeshiurban
womentowardsthe Pap test. A questionnaire-based survey of 400 Bangladeshi urban women was evaluated by on their
socio-demographic characteristics, knowledgeand attitudes towards Pap testing. In general, the findings reveal that
respondents havea good understanding of thepurpose of Pap test screening with 3.92 (Mean score). With 3.54 Mean
score,the respondents believed that Pap tests are recommended to women who are married and with 3.45 mean score
women believed that Pap tests arerecommended only to those who have children. Generally, respondents possess good
knowledge of Pap test and its purpose. These findings can be used in identifying prospect cervical cancer screening
significance populations and trend for future intrusion.
Fulltext Climate change induced human displacement in Bangladesh: Implications on the livelihood of displaced riverine island dwellers and their adaptation strategies

Hossain B, Shi G, Ajiang C, Sarker MNI, Sohel MS, Sun Z, et al.

Front Psychol, 2022;13:964648.
PMID: 36312059 DOI: 10.3389/fpsyg.2022.964648

In Bangladesh, many people are being displaced in riverine island (char) areas every year due to climate change and its associated natural catastrophes. This study intends to investigate the impact of climate change on internally displaced char people's lives and livelihoods along with local adaptation strategies and hindrances to the coping mechanism. Data have been collected from 280 internally displaced households in two sub-districts. A mixed-method approach has been considered combined with qualitative and quantitative methods. The results disclose that frequent flooding, riverbank erosion, and crop loss are the leading causes for relocation, and social relations are impeded in the new place of residence. Increasing summer and winter temperatures, recurrent flooding, severity of riverbank erosion, and expanding disease outbreaks are also important indicators of climate change identified by displaced people, which are consistent with observed data. This study also reveals that almost all households come across severe livelihood issues like food shortage, unemployment and income loss, and housing and sanitation problems due to the changing climate associated with disasters in the former and present places. In response to this, the displaced people acclimatize applying numerous adaptation strategies in order to boost the livelihood resilience against climate change. However, fragile housing, financial conditions, and lack of own land are still the highest impediments to the sustainability of adaptation. Therefore, along with the government, several organizations should implement a dynamic resettlement project through appropriate scrutiny to eradicate the livelihood complications of internally displaced people.
Fulltext Impacts of COVID-19 induced food insecurity among informal migrants: Insight from Dhaka, Bangladesh

Sohel MS, Hossain B, Sarker MNI, Horaira GA, Sifullah MK, Rahman MA

J Public Aff, 2021 Oct 29.
PMID: 34899062 DOI: 10.1002/pa.2770

Food insecurity is one of the rising problems in Bangladesh, and it is severely prevalent among informal migrant workers. In this case, the COVID-19 pandemic has multiplied the food insecurity of informal migrant workers. This study explores and synthesizes the COVID-19 induced food insecurity impact among informal migrants and recommends policy actions to tackle the COVID-19 led food crisis in Bangladesh. A qualitative research approach, including in-depth interviews, four FGDs, and participant observation, has been applied to data collection from different parts of Dhaka city. A thematic approach to interpretive phenomenological analysis is followed in this study. The results show that COVID-19 induced lockdown significantly affects informal migrants' household food security. Most participants report severe complications due to food insecurity like consuming less food, price hiking, no fish or meat, potato, and vegetable. Food insecurity leads to migrant's chronic food shortage, starvation, malnutrition of mother and children, and unhealthy food. As a result, the way of life of informal migrants has been directed to more fragility and vulnerability during the pandemic; even they are not affordable to maintain a minimal level of family affairs and necessity. The findings of this study would be essential guidelines for the governmental and non-governmental organizations and development practitioners to address the food insecurity situations.
Fulltext Genotypic to Phenotypic Resistance Discrepancies Identified Involving β-Lactamase Genes, blaKPC, blaIMP, blaNDM-1, and blaVIM in Uropathogenic Klebsiella pneumoniae

Urmi UL, Nahar S, Rana M, Sultana F, Jahan N, Hossain B, et al.

Infect Drug Resist, 2020;13:2863-2875.
PMID: 32903880 DOI: 10.2147/IDR.S262493

Introduction: Klebsiella pneumoniae carbapenemase (KPC) belongs to the Group-A β-lactamases that incorporate serine at their active site and hydrolyze various penicillins, cephalosporins, and carbapenems. Metallo-beta-lactamases (MBLs) are group-B enzymes that contain one or two essential zinc ions in the active sites and hydrolyze almost all clinically available β-lactam antibiotics. Klebsiella pneumoniae remains the pathogen with the most antimicrobial resistance to KPC and MBLs.
Methods: This research investigated the blaKPC, and MBL genes, namely, blaIMP, blaVIM, and blaNDM-1 and their phenotypic resistance to K. pneumoniae isolated from urinary tract infections (UTI) in Bangladesh. Isolated UTI K. pneumoniae were identified by API-20E and 16s rDNA gene analysis. Their phenotypic antimicrobial resistance was examined by the Kirby-Bauer disc diffusion method, followed by minimal inhibitory concentration (MIC) determination. blaKPC, blaIMP, blaNDM-1, and blaVIM genes were evaluated by polymerase chain reactions (PCR) and confirmed by sequencing.
Results: Fifty-eight K. pneumoniae were identified from 142 acute UTI cases. Their phenotypic resistance to amoxycillin-clavulanic acid, cephalexin, cefuroxime, ceftriaxone, and imipenem were 98.3%, 100%, 96.5%, 91.4%, 75.1%, respectively. Over half (31/58) of the isolates contained either blaKPC or one of the MBL genes. Individual prevalence of blaKPC, blaIMP, blaNDM-1, and blaVIM were 15.5% (9), 10.3% (6), 22.4% (13), and 19% (11), respectively. Of these, eight isolates (25.8%, 8/31) were found to have two genes in four different combinations. The co-existence of the ESBL genes generated more resistance than each one individually. Some isolates appeared phenotypically susceptible to imipenem in the presence of blaKPC, blaIMP, blaVIM, and blaNDM-1 genes, singly or in combination.
Conclusion: The discrepancy of genotype and phenotype resistance has significant consequences for clinical bacteriology, precision in diagnosis, the prudent selection of antimicrobials, and rational prescribing. Heterogeneous phenotypes of antimicrobial susceptibility testing should be taken seriously to avoid inappropriate diagnostic and therapeutic decisions.