Displaying all 3 publications

Abstract:
Sort:
  1. Leong LK, Zuhdi ASM, Hafidz MIA
    Singapore Med J, 2021 Dec;62(12):653-658.
    PMID: 32460450 DOI: 10.11622/smedj.2020079
    INTRODUCTION: Clinical depression is a known consequence of acute coronary syndrome (ACS) and is associated with an adverse outcome among these patients, although this is often under-recognised. Through this study, we investigated the incidence of depression in post-ACS patients and its associated factors.

    METHODS: We conducted a prospective cohort study in 95 patients with ACS admitted to University Malaya Medical Centre, Malaysia. Clinical depression was assessed during the index admission and at 30 days after discharge, using the Patient Health Questionnaire-9 (PHQ-9). Data was analysed using IBM SPSS Statistics, and binary logistic regression was used to determine the independent factors associated with depression, after adjusting for significant demographic variables and clinical characteristics. The strength of this association was presented as odds ratio and 95% confidence interval, and the significance level was set at 0.05.

    RESULTS: The mean age of the study population was about 60 years, and 72.6% of the patients were male. Symptoms of depression were present in 88.4% of the patients at baseline. Depression at 30 days was more likely in female patients, patients with diabetes mellitus and patients on dialysis (p = 0.024, p < 0.001, p = 0.008, respectively). Patients with baseline moderate to severe depression were more likely to have moderate to severe depression at 30 days (p < 0.001). Baseline depression was the strongest predictor of depression at 30 days. An increment of one unit in PHQ-9 baseline score increased the risk of developing severe depression at 30 days by 31%.

    CONCLUSION: Depression was prevalent in our post-ACS patients. The associated factors were female gender, diabetes mellitus and dialysis treatment.

  2. Ying LY, Ramoo V, Ling LW, Nahasaram ST, Lei CP, Leong LK, et al.
    Nurs Crit Care, 2021 11;26(6):432-440.
    PMID: 32929840 DOI: 10.1111/nicc.12551
    BACKGROUND: Retaining experienced critical care nurses (CCNs) remains a challenge for health care organizations. Nursing practice environment and resilience are both seen as modifiable factors in ameliorating the impact on CCNs' intention to leave and have not yet been explored in Malaysia.

    AIMS AND OBJECTIVES: To assess the association between perceived nursing practice environment, resilience, and intention to leave among CCNs and to determine the effect of resilience on intention to leave after controlling for other independent variables.

    DESIGN: This was a cross-sectional survey.

    METHODS: The universal sampling method was used to recruit nurses from adult and paediatric (including neonatal) critical care units of a large public university hospital in Malaysia. Descriptive analysis and χ2 and hierarchical logistic regression tests were used to analyse the data.

    RESULTS: A total of 229 CCNs completed the self-administrated questionnaire. Of the nurses, 76.4% perceived their practice environment as being favourable, 54.1% were moderately resilient, and only 20% were intending to leave. The logistic regression model explained 13.1% of variance in intention to leave and suggested that being single, an unfavourable practice environment, and increasing resilience were significant predictors of nurses' intention to leave.

    CONCLUSION: This study found that an unfavourable practice environment is a strong predictor of intention to leave; however, further exploration is needed to explain the higher likelihood of expressing intention to leave among CCNs when their resilience level increases.

    RELEVANCE TO CLINICAL PRACTICE: Looking into staff allocation and equality of workload assignments may improve the perception of the work environment and help minimize intention to leave among nurses.

  3. Liang TY, Senthil Raja D, Chin KC, Huang CL, Sethupathi SA, Leong LK, et al.
    ACS Appl Mater Interfaces, 2020 Apr 01;12(13):15183-15193.
    PMID: 32167283 DOI: 10.1021/acsami.0c00086
    Syngas, consisting of equimolar CO and H2, is an important feedstock for large-scale production of a wide range of commodity chemicals including aldehyde, methanol, ammonia, and other oxygenated chemicals. Dry reforming of methane (DRM), proceeding by reacting greenhouse gases, CO2 and CH4, at high temperatures in the presence of a metal catalyst, is considered one of the most environmentally friendly routes for syngas production. Nevertheless, nonprecious metal-based catalysts, which can operate at relatively low temperatures for high product yields and selectivities, are required to drive the DRM process for industrial applications effectively. Here, we developed NiCo@C nanocomposites from a corresponding NiCo-based bimetallic metal-organic framework (MOF) to serve as high-performance catalysts for the DRM process, achieving high turnover frequencies (TOF) at low temperatures (>5.7 s-1 at 600 °C) and high product selectivities (H2/CO = 0.9 at 700 °C). The incorporation of Co in Ni catalysts improves the operation stability and light-off stability. The present development for MOF-derived nanocomposites opens a new horizon for design of DRM catalysts.
Related Terms
Filters
Contact Us

Please provide feedback to Administrator (afdal@afpm.org.my)

External Links