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  1. Comparative evaluation of the effectiveness of desensitizing agents in dentine tubule occlusion using scanning electron microscopy
    Chen CL, Parolia A, Pau A, Celerino de Moraes Porto IC
    Aust Dent J, 2015 Mar;60(1):65-72.
    PMID: 25721280 DOI: 10.1111/adj.12275
    Dentine hypersensitivity (DH) occurs on exposed dentine and is dependent on the patency of dentinal tubules. This study compared the effectiveness of red propolis extract (RPE), calcium sodium phosphosilicate (Novamin) and arginine-calcium carbonate (ACC) in occluding dentine tubules.
  2. A comparative evaluation of microleakage around class V cavities restored with different tooth colored restorative materials
    Parolia A, Adhauliya N, de Moraes Porto IC, Mala K
    Oral Health Dent Manag, 2014 Mar;13(1):120-6.
    PMID: 24603928
    To evaluate and compare microleakage around class V cavities restored with silorane and dimethacrylate-based composite resins.
  3. Fulltext A comparative effect of various surface chemical treatments on the resin composite-composite repair bond strength
    Gupta S, Parolia A, Jain A, Kundabala M, Mohan M, de Moraes Porto IC
    J Indian Soc Pedod Prev Dent, 2015 Jul-Sep;33(3):245-9.
    PMID: 26156281 DOI: 10.4103/0970-4388.160402
    The aim of this in vitro study was an attempt to investigate the effect of different surface treatments on the bond strength between pre-existing composite and repair composite resin.
  4. Fulltext Comparative radiopacity of six current adhesive systems
    de Moraes Porto IC, Honório NC, Amorim DA, de Melo Franco AV, Penteado LA, Parolia A
    J Conserv Dent, 2014 Jan;17(1):65-9.
    PMID: 24554865 DOI: 10.4103/0972-0707.124151
    The radiopacity of contemporary adhesive systems has been mentioned as the indication for replacement of restorations due to misinterpretation of radiographic images.
  5. Fulltext Brazilian red propolis: phytochemical screening, antioxidant activity and effect against cancer cells
    de Mendonça IC, Porto IC, do Nascimento TG, de Souza NS, Oliveira JM, Arruda RE, et al.
    BMC Complement Altern Med, 2015 Oct 14;15:357.
    PMID: 26467757 DOI: 10.1186/s12906-015-0888-9
    BACKGROUND: The implementation of new public healthcare models that stimulate the use of natural products from traditional medicine, as a so-called integrated medicine, refers to an approach that use best of both conventional medicine and traditional medicine. Propolis is a widely used natural product by different ancient cultures and known to exhibit biological activities beneficial for health. The large number of studies conducted with propolis had shown that its chemical composition differs as a function of the climate, plant diversity and bee species and plays an important role on its therapeutic properties. The aim of this study was to analyse the phytochemical profile of the ethanolic extract of red propolis (EEP) and its fractionation, antioxidant action of EEP and its fractions hexane, cloroform and ethyl acetate and cytotoxic activity of EEP on human tumour cell lines SF-295 (glioblastoma), OVCAR-8 (ovary) and HCT-116 (colon).

    METHODS: EEP was obtained by maceration with absolute ethanol, then it was concentrated in rotaevaporator up to complete evaporation of the solvent. The crude extract was fractionated with hexane, ethyl acetate, chloroform and methanol and they were subjected to phytochemical screening and total phenolic compounds. Antioxidant activity of EEP and fractions was done by means of the 2,2-diphenyl-1-picryhydrazyl (DPPH) method. Biomarkers of red propolis were identified by LC-Orbitrap-FTMS. To assess cytotoxic activity of the extract, cells were exposed to EEP over 72 h. Cell viability was assessed by means of MTT assay. The percentage of cell growth inhibition (IC50) was analysed by means of non-linear regression, and the absorbance values of the various investigated concentrations were subjected to one-factor analysis of variance (ANOVA) followed by Tukey's or Tamhane's tests (α = 0.05).

    RESULTS: The results obtained using phytochemical screening and LC-Orbitrap-FTMS indicated the presence of phlobaphene tannins, catechins, chalcones, aurones, flavonones, flavonols, xanthones, pentacyclic triterpenoids and guttiferones in Brazilian red propolis. EEP and its hexane, chloroform and ethyl acetate fractions obtained by liquid-liquid partitioning exhibited satisfactory antioxidant percentages. EEP (IC50 

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