This paper presents an effective approach for the optimization of an in-feed centreless cylindrical grindingof EN52 austenitic grade steel (DIN: X45CrSi93) with multiple performance characteristics based on thegrey relational analysis. To study the effect of the entire space of the input variables, nine experimentalruns, based on the Taguchi method of L9 orthogonal arrays, were performed to determine the best factorlevel condition. The response table and response graph for each level of the machining parameters wereobtained from the grey relational grade. In this study, the in-feed centreless cylindrical grinding processparameters, such as dressing feed, grinding feed, dwell time and cycle time, were optimized by takinginto consideration the multiple-performance characteristics like surface roughness and out of cylindricity.By analyzing the grey relational grade, it was observed that dressing feed, grinding feed and cycle timehad significant effect on the responses. The optimal multiple performance characteristics were achievedwith dressing feed at level 1 (5 mm/min), grinding feed at level 2 (6 mm/min), dwell time at level 2(2.5 s), and cycle time at level 2 (11 s). It is clearly shown that the above performance characteristics inthe in-feed Centreless cylindrical grinding process can be improved effectively through this approach.