This study aimed to integrate polyether sulfone (PES) membrane with hydroxyapatite synthesized from fish scale biowaste (HAp) to form ion exchange membrane. The PES incorporated by self-assembled with different concentrations of HAp solution; 0.2, 0.4, 0.6, 0.8 and 1.0 wt%. The prepared ion exchange membranes were characterized regarding permeability coefficient, porosity, morphology, ion exchange capacity (IEC), AT-IR, and fouling analysis. The promising characteristics and outstanding performance demonstrated by PES membrane incorporated with 0.8 wt%. Via SEM images and ATIR spectra, the PES/HAp-0.8 membrane depicted the adequate number, well distributed and low agglomeration of HAp onto the membrane surface with a strong attachment. The membrane also demonstrated good ion exchange capacity around 49%. Permeability coefficient for PES/HAp-0.8 membrane was 101.5 L/m2.h with 87.69 % membrane porosity.