Organotin compounds especially the dialkyltin derivatives are reported to possess anti-tumour properties. The diorganotin(IV) complexes of the type Me2SnL1, Me2SnL2, Bu2SnL1, Bu2SnL2 and Ph2SnL1 (L1 and L2 is the anion of the thiosemicarbazone ligand formed by the condensation reaction of 2,3-dihydroxybenzaldehyde with thiosemicarbazide or its N(4)-methyl substituent) were synthesized using 1:1 metal-to-ligand reactant ratios. The newly synthesized complexes were characterized using elemental analysis, infrared and nuclear magnetic resonance (1H, 13C, 119Sn) spectroscopic techniques. Complex formation between the organotin(IV) moiety and the anions of 2,3-dihydroxybenzaldehyde thiosemicarbazone and 2,3-dihydroxybenzaldehyde 4-methylthiosemicarbazone occurred with chelation at the o-dihydroxy positions. The complexes are proposed to have tetrahedral geometry.
Organostannum(IV) complexes derived from dicarboxylic acids have been successfully synthesised from triphenylstannum(IV) hydroxide (Ph3SnOH). The complexes were obtained by refluxing Ph3SnOH and the respective dicarboxylic acids (malonic, succinic, glutaric and adipic acids) using a Dean and Stark apparatus in the appropriate solvent. The free ligands and complexes were characterised by C, Hand Sn elemental analysis and spectroscopic methods such as infrared and nuclear magnetic resonance (1H, 13C NMR). Structure determination of triphenylstannum(IV) succinate, 2, showed that each dicarboxylate anion was bonded monodentatically to two triphenylstannum(IV) moieties. The geometry surrounding each stannum atom is close to a tetrahedron. Spectroscopic data obtained for all complexes were found to be similar and thus it may be concluded that all complexes have the same structure as 2.
New organotin(IV) sec-butylpropyldithiocarbamate complexes have been sucÂcessfully synthesized by the reaction between N-sec-butyl-N-propylamine, carbon disulfide and organotin(IV) chloride (dimethyltin(IV), dibutyltin(IV) and triphenyltin(lV) chloride) using in-situ method. All the complexes have been characterized using elemental analysis, gravimetric analysis, infrared and NMR (1H and I3C) spectroscopy. Elemental and gravimetric analyses showed that the complexes agree with the suggested formulae, R2Sn[S2CN( sÂC4H9)(C3H7)]2 dan R‘3Sn[S2CN(s-C4H9)(C3H7)] (R = CH3 or R = C4H9; R' = C6H5 The presence of the v(C = N) and v(C = S) bands in the infrared spectra confirmed the presence of dithiocarbamate ligand in that complex. The 13C NMR spectra for all the complexes showed a resonance in the region 196.22 - 200.62 ppm, which is attributed to the carbon atom of NCS2 group. The dimethyltin(lV) sec-butylpropyldithiocarbamate, Me2Sn(SBPDtc)2 was recrystallized from CHCl3 and the structure had been determined using X-ray crystallography analysis. The structure of Me2Sn[s-C4H9)(C3H7)]2 is found to be in the monoclinic system with space group P21/n, a = 14.358(2), b = 10.6956(18), c = 17.323(3) Ã…; α = 90°, β = 99.765(4)°, γ = 90°. The complex is six-coordinated with the tin atom bonded by two dimethyl groups in cis positions and two chelating sec-butylpropyldithiocarbamates in bidentate mode.
Kompleks baru organostanum(IV) sek-butilpropilditiokarbamat telah berjaya disediakan melalui tindak balas di antara N-sek-butil-N-propilamina, karbon disulfida dan sebatian dimetilstanum(lv), dibutilstanum(IV) dan trifenilstanum(IV) klorida menggunakan kaedah in-situ. Kesemua kompleks telah dicirikan menggunakan analisis unsur, analisis gravimetri, spektroskopi inframerah dan spektroskopi resonans magnet nukleus 1H dan 13C. Analisis unsur (CHNS) dan gravimetri menunjukkan sebatian yang disintesis bersetuju dengan formula yang dicadangkan, iaitu R2Sn[S2CN(s-C4H9)(C3H7)]2 dan R'3Sn[S2CN(s-C4H9)(C3H7] (R = CH3 atau C4H9; R' = C6H5). Kehadiran jalur serapan v(C ---- N) dan v(C ---- S) pada spektrum inframerah menunjukkan kehadiran ligan ditiokarbamat dalam sebatian yang disediakan. Spektrum RMN I3C bagi ketiga-tiga kompleks menunjukkan resonan N13CS2 terletak pada julat 196.22- 200.61 ppm. Kompleks dimetilstanum(1V) sekÂbufilpropilditiokarbamat telah berjaya dihablurkan menggunakan pelarut kloroform. Kajian kristalograji sinar-X menunjukkan hablur Me2Sn[s-ÂC4H9)(C5H7)]2 bersistem monoklinik dengan kumpulan ruang P21/n, a = 14.358(2), b = 10.6956(18), c = 17.323(3) Ã…; α = 90°, β= 99.765(4)°, γ = 90°. Kompleks membentuk geometri enam koordinat dengan atom pusat stanum yang berikat dengan dua kumpulan metil pada kedudukan sis dan mengkelat secara bidentat dengan ligan sek-butil propilditiokarbamat.
An ethanolic solution of caffeine was added to an aqueous solution of metal salts and followed by adding ethanolic solution of adenine and an aqueous solution of potassium thiocyanate to give complexes with general formula [M(CA)2(Ad)X2] where CA is caffeine, Ad is adenine, X is thiocyanate ion and M is Co(II), Ni(II), Cu(II), Zn(II) and Cd(II). The resulting products were characterized using UV-visible and infrared spectroscopies. Elemental analyses were performed using C, H, N analysis and atomic absorption techniques. The magnetic susceptibility and the conductivity were also measured. The results suggested that the complexes have octahedral geometry.
Aluminium in drinking water comes from natural sources and the alum used as coagulant in the water treatment process. Exposure to aluminium has been implicated in dialysis dementia, Parkinson and Alzheimer’s disease. Drinking water containing aluminium was considered to be one of the main sources of Al intake into human body. For this reason, the removal of aluminium from drinking water is vital to our health. In this study, removal of aluminium was carried out by using a chelating resin. To achieve the purpose, two chelating resin iontosorb oxin (IO) and polyhydroxamic acid (PHA) were used. The effects of concentration, pH, stirring time and resin amount was investigated. The concentration range varied between 10 and 500 ppb, pH range was between 2 and 12, stirring time between 5 and 60 minutes, and resin amount between 100 and 1500 mg. The optimum conditions of these resins were determined in a batch system. The results obtained showed that the optimum condition to remove aluminium for polyhydroxamic acid and iontosorb was pH 5-8 and pH 4-9; concentration range between 50-500 ppb, and 150-500 ppb, resin amount 200 mg and the stirring time was 20 minutes, respectively.
Loji rawatan kumbahan (STP) sedia ada khususnya di Malaysia tidak direka untuk menyingkirkan bahan farmaseutik yang
tergolong dalam kategori bahan cemar baru muncul. Oleh kerana farmaseutik yang hadir dalam persekitaran akuatik
ialah pada kepekatan yang sangat rendah iaitu dalam julat bahagian per bilion dan trilion, satu kaedah pengekstrakan
dan analisis yang peka perlu dibangunkan. Dalam kajian ini, kaedah analisis berdasarkan pengekstrakan fasa pepejal
(SPE) diikuti dengan kromatografi cecair-spektrometri jisim masa penerbangan (LC-TOF-MS) menggunakan mod pengionan
secara semburan elektro positif telah berjaya dibangunkan untuk menentukan kehadiran sepuluh farmaseutik terpilih
dalam air kumbahan dan air sungai. Farmaseutik yang dikaji termasuk acetaminophen, theophylline, caffeine, metoprolol,
sulfamethoxazole, carbamazepine, prednisolone, ketoprofen, norgestrel dan simvastatin. Kaedah SPE menggunakan
langkah pengekstrakan tunggal yang menggunakan isi padu sampel yang rendah sebanyak 100 mL dan pelarut elusi
yang minimum telah berjaya dicapai. Peratus perolehan semula untuk kesemua farmaseutik dalam sampel air sungai
berada dalam julat 54-99% manakala bagi sampel efluen STP pula berada dalam julat 57-96%. Jangka masa analisis
LC-TOF-MS termasuk masa imbangan adalah selama 25 min dengan menggunakan suntikan sampel 20 μL. Prosedur SPE
bersama-sama dengan kaedah analisis yang telah dibangunkan menghasilkan had kuantifikasi (LOQ) dalam lingkungan
0.031-0.882 μg/L untuk sampel STP dan 0.030-0.926 µg/L untuk sampel air sungai.
Several triphenylphosphinosilver (I) complexes, viz. bis [acetatotriphenylphosphineargentum (I)], I, lactatotris (triphenylphosphine) argentum (I), II, N, N-diethanoldithiocarbamatobis (triphenylphosphine) silver (I), III, and NÂethanol, N-methyldithiocarbamatobis (triphenylphosphine) silver (I), IV, have been prepared. Apart from characterization by spectroscopic methods, the structures of I-III, have been characterised by single-crystal x-ray diffraction methods. I crystallized as a dimer with a 4-coordinate geometry around the silver atom, while the lactate complex is a monomer with a five-coordinate silver atom. In the four-coordinate complex III, the Ag - S bond distances are 2.6822 (13) and 2.5991 (12) Ã… indicating different modes of bonding to the dithiocarbamate ligands.
Beberapa kompleks trifenilfosfinoargentum telah disintesis, iaitu bis [asetatotrifenilfosfinargentum (I)], I, laktatotris (trifenilfosfin) argentum (I), II dietanolditiokarbamatobis (trifenilfosfin) argentum (I), III dan metiletanolditiokarbamatobis (trifenilfosfin) argentum (I), IV. Selain daripada pencirian dengan kaedqh spektroskopi, struktur kompleks I-III telah ditentukan dengan kaedah pembelauan sinar-X hablur tunggal. Kompleks asetat terhablur sebagai dimer dengan argentum menunjukkan geomertri 4-koordinat, sementara kompleks laktat adalah monomer dengan argentum berkoordinatan lima. Dalam kompleks dietanolditiokarbamat argentum berkoordinatan empat dengan panjang ikatan Ag - S, 2.6822 (13) dan 2.5991 (12) Ã… menunjukkan dua mod pengikatan yang berbeza dengan ditiokarbamat.
Two adducts of bis(N-benzyl-N-isopropyldithiocarbamato) zinc(II) with 2,2'Â-bipyridine and 1,10-phenanthroline have been successfully synthesized and characterized by elemental analysis and spectroscopic studies. The IR specÂtra of these adducts showed the thioureide band, v(C---- N) which occurred at 1440 and 1438 cm-1 respectively, lower than the parent compound at 1471 cm-1. The 13C NMR spectroscopic data for these compounds showed that the carbon signal from CS2 moiety shifted slightly downfield to 206.6 and 208.5 ppm compared to the parent compound at 205.1 ppm. The single crystal structure of bis (N-benzyl-N-isopropyldithiocarbamato )zinc(II)(bipy) has been determined. The structure of this compound showed monomeric nature with hexacoordination of the metal in a highly distorted octahedral geometry.
Dua sebatian aduk zink(II) benzilisopropilditiokarbamat dengan ligan 2,2-bipiridil dan 1,10-fenantrolin telah berjaya disediakan dan dianalisis menggunakan analisis unsur dan kaedah spektroskopi. Spektrum IR untuk kedua-dua sebatian aduk ini telah menunjukkan kehadiran jalur tioureida, V(C----- N) pada 1440 dan 1438 cm-1 masing-masing yang mana jalur serapan ini didapati teranjak pada nilai yang lebih rendah berbanding sebatian asalnya iaitu pada 1471 cm-1. Data RMN 13C pula menunjukkan kehadiran signal karbon CS2 yang teranjak sedikit ke medan yang lebih rendah iaitu pada 206.6 dan 208.5 ppm masing-masing jika dibandingkan dengan sebatian asalnya pada 205.1 ppm. Struktur hablur tunggal bagi sebatian bis( N-benzilÂ-N-isopropilditiokarbamat)zink(11)(bipy) telah ditentukan. Struktur sebatian ini didapati bersifat monomerik dan berkoordinat enam dengan atom logam pusatnya mempunyai geometri oktahedron yang sangat terherot.
The title compound, [Sn(CH(3))(2)(C(5)H(10)NO(2)S(2))(2)], has crystallographic mirror symmetry (C-Sn-C on mirror plane) and the coordination polyhedron around the Sn atom is a tetrahedron [C-Sn-C 139.3 (2) degrees and S-Sn-S 82.3 (1) degrees ] distorted towards a skew-trapezoidal bipyramid owing to an intramolecular Sn.S contact [3.0427 (6) A]. The molecules are linked into a linear chain by intermolecular O-H.O hydrogen bonds [O.O 2.646 (3) A].