MyMedR

The effect of selected plant extracts on the development of single-species dental biofilms

Abdul Rahim ZH, Shaikh S, Hasnor Wan Ismail WN, Wan Harun WH, Razak FA

J Coll Physicians Surg Pak, 2014 Nov;24(11):796-801.

PMID: 25404435 DOI: 11.2014/JCPSP.796801

To determine the effect of a mixture of plant extracts on the adherence and retention of bacteria in dental biofilm.

Giant Urethral Calculus without Acute Urinary Retention

Abidin ZAZ, Hayati F, Tan GH, Goh EH, Hafidzul J, Zulkifli MZ

J Coll Physicians Surg Pak, 2018 Mar;28(3):S69-S70.

PMID: 29482714 DOI: 10.29271/jcpsp.2018.03.S69

A 46-year gentleman presented with a left-sided lumbar region pain without fever or dysuria. He denied episodes of acute urinary retention. There was a hard mass at the distal urethra with normal laboratory blood tests. Computed tomography urogram revealed a concurrent left renal staghorn calculus and large distal urethral stone. The urethral stone was fragmented via endourologic technique successfully. We report a case of a non-obstructing large urethral calculus in a gentleman with concurrent left renal staghorn calculus and discuss the literature review.

Atrial septal defect coexistent with Sjögren's syndrome

Ahmad F, Sadiq MA, Chee KH, Mahmood Zuhdi AS, Wan Ahmad WA

J Coll Physicians Surg Pak, 2014 Jun;24(6):441-3.

PMID: 24953923 DOI: 06.2014/JCPSP.441443

Pulmonary hypertension is frequently associated with atrial septal defect and various connective tissue disorders. This case describes a 74-year-old woman who presented with symptoms of heart failure and concomitant involvement of salivary glands and keratoconjunctivitis. An echocardiogram demonstrated ostium secundum atrial septal defect with left to right shunt and severe pulmonary hypertension. Laboratory investigations confirmed the diagnosis of Sjögren's syndrome (SS) with positive anti-nuclear factor and centromere SS-A/Ro pattern. Anti-Ro (SS-A) was found positive. Atrial septal defect was closed through transcatheter route with significant improvement in clinical outcome. This case report suggests a possible association of atrial septal defect with primary Sjögren's syndrome in an adult patient.

Mediterranean glucose-6-phosphate dehydrogenase (G6PD(C563T)) mutation among Jordanian females with acute hemolytic crisis

Al-Alimi AA, Kanakiri N, Kamil M, Al-Rimawi HS, Zaki AH, Yusoff NM

J Coll Physicians Surg Pak, 2010 Dec;20(12):794-7.

PMID: 21205543 DOI: 12.2010/JCPSP.794797

OBJECTIVE:
To evaluate the G6PD(C563T) Mediterranean mutation among Jordanian females who were admitted to Princess Rahma Teaching Hospital (PRTH) with/or previous history of favism.
STUDY DESIGN:
A descriptive study.
PLACE AND DURATION OF STUDY:
Jordanian University of Science and Technology and PRTH, from October 2003 to October 2004.
METHODOLOGY:
After obtaining approval from the Ethics Committee of Jordanian University of Science and Technology, a total of 32 females were included in this study. Samples from 15 healthy individual females were used as a negative control. Blood samples from these patients were collected and analyzed by allele-specific polymerase chain reaction (AS-PCR) to determine the G6PD(C563T) mutation.
RESULTS:
Twenty one out of 32 patients were found to be G6PD(C563T) Mediterranean mutation (65.6%) positive. Three out of 21 patients were homozygous and remaining 18 were heterozygous for G6PD(C563T) Mediterranean mutation. Eleven (34.4%) out of 32 patients were found to be negative for G6PD(C563T) mutation indicating the presence of other G6PD mutations in the study sample.
CONCLUSION:
G6PD(C563T) Mediterranean mutation accounted for 65.6% of the study sample with favism in the North of Jordan. There is likely to be another G6PD deficiency variant implicated in acute hemolytic crisis (favism).

A Single Institution's Experience with Cytogenetic and MRD Outcomes in Pediatric Acute Lymphoblastic Leukemia

Amjad A, Wali RM, Anjum S, Mansoor R

J Coll Physicians Surg Pak, 2019 Jun;29(6):549-552.

PMID: 31133155 DOI: 10.29271/jcpsp.2019.06.549

OBJECTIVE: To determine the frequency of cytogenetic type and its significance in the prognostic outcome of the pediatric patients in acute lymphoblastic leukemia (ALL), aged 1 to 15 years, and also determine the importance of minimal residual disease (MRD) in the management of the condition.

STUDY DESIGN: An observational study.

PLACE AND DURATION OF STUDY: Pediatric Oncology Ward, Shaukat Khanum Cancer Hospital, Lahore, from January 2015 to July 2017.

METHODOLOGY: Patients aged 1-15 years, diagnosed with ALL, were included. Studied variables were cytogenetic type and MRD outcome in patients with ALL. Patients under one year of age and more than 15 years, or those having comorbidities, were excluded.

RESULTS: Total 150 patients' data were retrieved from the Hospital database. One hundred and thirty-three belonged to age 1 to 5 years group (89%) and 17 (11%) were in 5 to 10 years group. The mean age of the patient was 4.3 +3.1 years. One hundred and two (68%) were males; whereas, 48 (32%) were females. Pre B acute lymphoblastic leukemia was diagnosed in 139 (93%) patients and 11(7%) were diagnosed with Pre T acute lymphoblastic leukemia. Standard risk was observed in 120 (80%) patients and 30 (20%) patients were on high risk as per National Cancer Institute (NCI) Guidelines. Regimen A was used in 125 (83.3%), Regimen B in 16 (10.7%), and Regimen C in 9 (6%) patients. BCR-ABL was positive in 2 (1.30%), TEL-AML in 68 (45%), MLL in 5 (3.30%), and normal in 54 (36%). MRD at day 29 was negative in 40 (93%) and positive in 3 (7%). The karyotyping was done in 128 (85%) patients, out of which 68 (53%) were hyperploids, 41 (32%) euploid, and 19 (15%) were hypoploid. Death was observed in 22 (15%) patients. Nineteen (86%) deaths were due to fungal and bacterial sepsis; and disease-related deaths were noted in 3 (14%) patients.

CONCLUSION: The role of MRD and cytogenetics in risk assessment has improved in the early prognosis determination.

Unicystic Ameloblastoma: A Perception for the Cautious Interpretation of Radiographic and Histological Findings

Arora S

J Coll Physicians Surg Pak, 2015 Oct;25(10):761764-764.

PMID: 26454399 DOI: 10.2015/JCPSP.761764

The term Unicystic Ameloblastoma (UA) refers to those cystic lesions that show clinical and radiological characteristics of an odontogenic cyst but on histological examination show a typical ameloblastomatous epithelium lining part of the cyst cavity, with or without luminal and/or mural tumor growth. Till date, lot of controversies exist among oral surgeons and oral pathologists regarding this entity. An attempt is being made here to discuss all the diagnostic dilemmas associated with UA.

Temporomandibular Joint Disorders: Is there a Need for Additional Subspeciality in Dentistry?

Arshad S, Awang RA, Malik S

J Coll Physicians Surg Pak, 2021 Aug;31(8):1004.

PMID: 34320727 DOI: 10.29271/jcpsp.2021.08.1004

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Dentist-nephrologist symbiosis in the dental management of chronic kidney disease patient

Chidambaram R

J Coll Physicians Surg Pak, 2014 Dec;24(12):955.

PMID: 25523738 DOI: 12.2014/JCPSP.955955

The Probability of Resistant Hypertension During Dental Treatment of Chronic Kidney Disease Patients

Chidambaram R

J Coll Physicians Surg Pak, 2017 Jan;27(1):44-46.

PMID: 28292368 DOI: 2520

Oral rehabilitation in medically compromised patients like chronic kidney disease (CKD) needs special dental care. Many papers have been published on dental considerations for such individuals. However, literature citing oral care for patients with risk factors of CKD are scarce. Resistant hypertension, one such risk factor, is closely related to CKD. Furthermore, the associated increased prevalence and adverse renal/cardiac outcomes motivated the author to report its unexplored association/impact during dental care. The importance of assessing glomerular filtration rate is highlighted to better understand patients' medical conditions.

Cardiologist-Dentist Interaction in the Dental Management of Immunocompromised Cardiac Patient

Chidambaram R

J Coll Physicians Surg Pak, 2017 Apr;27(4):261.

PMID: 28492161 DOI: 2604

New Evidence Showing yet another Link between Sight-Threatening Diabetic Retinopathy and Obstructive Sleep Apnea: How Relevant is this to my General Practice?

Chidambaram R

J Coll Physicians Surg Pak, 2018 Nov;28(11):893.

PMID: 30369389 DOI: 10.29271/jcpsp.2018.11.893

Important Decision for an Oral Physician to Make in High-Risk Chronic Kidney Disease Patients: It is Not Only to Recordthe Associated Resistant Hypertension, but Whether to Use Manual Sphygmomanometer or Automated Blood Pressure Device?

Chidambaram R

J Coll Physicians Surg Pak, 2018 Feb;28(2):169.

PMID: 29394983 DOI: 10.29271/jcpsp.2018.02.169

Good News: Dentists are Competent in Diagnosing Undiagnosed Sleep Apnea

Chidambaram R

J Coll Physicians Surg Pak, 2017 May;27(5):321.

PMID: 28599700 DOI: 2624

Increased Risk of Dental Issues in Type II Diabetics

Chidambaram R

J Coll Physicians Surg Pak, 2018 Jan;28(1):86.

PMID: 29290207 DOI: 10.29271/jcpsp.2018.01.86

Multidisciplinary Approach for Management of a Patient with Oral Mucosal Malignant Melanoma

Eachempati P, Aggarwal H, Shenoy VK, Baliga M

J Coll Physicians Surg Pak, 2018 Sep;28(9):S187-S189.

PMID: 30173693 DOI: 10.29271/jcpsp.2018.09.S187

Oral mucosal melanoma is rare and more aggressive than cutaneous melanoma. Hard palate and maxillary alveolar crest are most commonly involved. Multidisciplinary team approach is necessary for successful management of this tumor. The main treatment modality is surgical resection, which usually results in impaired mastication, deglutition, speech, oral competence and significant cosmetic deformity. Here, a rare case of oral mucosal melanoma of mandibular gingiva in a 44-year man is reported, who was treated by en-block mandibular resection followed by adjuvant therapy with high dose interferons (IFN) - 2b. Following two weeks of healing period, prosthetic rehabilitation of the patient was done with an interim removable denture prosthesis, which effectively limited the unfavourable effects of surgery and helped him in resocialisation.

Multiple Small Bowel Atresia: Resection or Conservation?

Govindarajan KK, Annamalai M

J Coll Physicians Surg Pak, 2021 Jun;30(6):740-742.

PMID: 34102795 DOI: 10.29271/jcpsp.2021.06.740

Multiple small bowel atresia is a relatively uncommon cause of intestinal obstruction in neonates. About one-third of the neonatal intestinal obstruction is caused by intestinal atresia. As suggested by Louw and Barnard, the vascular accident in utero is the principal reason, resulting in bowel atresia.1 The condition presents soon after birth, with bilious vomiting and abdominal distension, requiring emergency surgical intervention. A subtype of small bowel atresia (type IV), which presents with involvement of multiple segments, is unique due to the difficulties in management, accompanied by a variety of postoperative morbidities, which are highlighted in this case. The choice lies between resection of all the atretic segments with resultant single anastomosis and conservation with anastomoses of multiple small bowel segments involving meticulous repair by fine sutures, taking care to maintain luminal patency. The dilemma of whether to conserve the atretic segments of bowel, which is a time consuming procedure but preserves the bowel length or to proceed with excision of the atretic bowel segments, accepting the likelihood of short bowel, in order to provide a quick, safe and stable single anastomosis in a timely manner, is a valid challenge. The background of limited resource setting also need to be taken into consideration. Key Words: Atresia, Neonates, Bowel segments, Anastomosis.

Intestinal Obstruction Due to Super Absorbent Polymer Bead Ingestion in Children

Govindarajan KK, Arasappan M

J Coll Physicians Surg Pak, 2023 Feb;33(2):232-233.

PMID: 36797637 DOI: 10.29271/jcpsp.2023.02.232

Ingested foreign bodies (Fb) in children usually pass out in stools without any sequels. However, Fbs like open safety pins, button batteries, and super absorbent polymer (SAP) / jelly toys are associated with complications such as intestinal obstruction, and bowel perforation. Intestinal obstruction in children of uncertain nature should raise a suspicion of foreign body ingestion such as SAP, which may not be obvious at the initial presentation. The study reports two such children, outlining the presentation and management. Key Words: Children, Intestinal obstruction, Foreign body, Health hazard, Bilious vomit, Super absorbent polymer beads.

Mushroom Bezoar Causing Small Bowel Obstruction

Hamzah AA, Keow CK, Syazri A, Mallhi TH, Khan AH, Khan YH, et al.

J Coll Physicians Surg Pak, 2017 Mar;27(3):S13-S15.

PMID: 28302231 DOI: 238

A bezoar is a concretion of foreign or indigestible matter in the alimentary canal and is usual cause of gastric obstruction. Bezoars can become fragmented and migrate downward leading to intestinal obstruction. Diagnosis of phytobezoar has become challenging in clinical practice due to lack of patient history and inability of patient to correlate preceding events with the episode of bowel obstruction. Bezoar associated small bowel obstruction rarely occurs and is usually found in patients with history of gastrointestinal surgery. Very few cases are reported of small bowel obstruction due to bezoar in healthy population without prior illness or surgery. We present a case of small bowel obstruction due to mushroom bezoar in a 62-year patient with no past history of medical illness or gastric surgery. Enterotomy was performed and a whole piece of undigested mushroom measuring 5 x 3 cm was successfully removed.

Comment to: Diagnostic Value of Serum Gastrin and Epidermal Growth Factor to the Gastric Ulcer Complicated with Upper Gastrointestinal Hemorrhage

Hayati F, Abdul Rahim MA, Abdul Rahim SSS

J Coll Physicians Surg Pak, 2021 Dec;31(12):1522-1523.

PMID: 34794305 DOI: 10.29271/jcpsp.2021.12.1522

Null.

Diagnostic Value of Preoperative Haemoglobin, Albumin, Lymphocyte and Platelet (HALP) Score in Predicting Tumour Budding in Colorectal Cancer

Hidrus A, Abdul Rahim SSS, Zakaria AD, Hayati F

J Coll Physicians Surg Pak, 2022 Nov;32(11):1514-1515.

PMID: 36377032 DOI: 10.29271/jcpsp.2022.11.1514

Null.

Displaying publications 1 - 20 of 52 in total