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  1. Fulltext Plasma ferritin, C-reactive protein, and adenosine deaminase levels in tuberculous lymphadenitis and pleuritis and their role in monitoring treatment response
    Nisa ZU, Zeshan B, Ambreen A, Mustafa T
    BMC Infect Dis, 2024 Dec 02;24(1):1375.
    PMID: 39623309 DOI: 10.1186/s12879-024-10228-z
    BACKGROUND: We aimed to assess the plasma levels of ferritin, C-reactive protein (CRP), and adenosine deaminase (ADA) at baseline and their utility as biomarkers to monitor response to treatment in extrapulmonary tuberculosis (EPTB) patients.

    METHODS: Prospective measurements of ferritin, CRP, and ADA were done in unstimulated plasma samples of 92 EPTB (49 TB lymphadenitis and 43 TB pleuritis) patients registered for anti-TB treatment. Blood samples were taken at the start, 2, and 6 months of treatment, plasma levels of ferritin and CRP were measured by the enzyme-linked immunosorbent assay and ADA levels by kinetic chemistry method at each time point. Data was analyzed using SPSS version 22. Non-parametric tests were used for paired analysis and two groups' comparison. Spearman's rank test was used for correlation analysis. A Chi-square test was used for categorical variables. A p-value 

    Matched MeSH terms: Tuberculosis, Pleural/drug therapy
  2. Significant resolution of tuberculous pleural effusion on chemotherapy alone
    Loh LC, Lim BK, Wan Yusuf S
    J R Coll Physicians Edinb, 2010 Jun;40(2):100-4.
    PMID: 21125048 DOI: 10.4997/JRCPE.2010.202
    As a standard, significant pleural effusion, whether tuberculous (TB) or not, requires therapeutic thoracocentesis. We tested the hypothesis that standard anti-TB chemotherapy alone can resolve significant pleural effusion.
    Matched MeSH terms: Tuberculosis, Pleural/drug therapy*
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