Introduction: Piper sarmentosum is one of the herbaceous plants that has been used as natural antioxidant to source to treat diseases. This study was conducted to determine the total phenolic contents (TPC) and free radical scavenging capacity in free and bound (soluble and insoluble) of P. sarmentosum. Methods: Free phenolic extract was acquired through direct methanol extraction while acidic and alkaline hydrolyses were adopted to release the bound phenolic acids. The TPC was determined by using Folin-Ciocalteu assay and is expressed as Gallic Acid equivalent (GAE) in miligrams per gram of extracts. The antioxidant scavenging capacity was determined by using DPPH (2, 2-diphenyl-1-picrylhydrazyl) assay. Results: Insoluble bound phenolic extract of P. sarmentosum showed the highest TPC value (1.54 ± 0.04 mg GAE/g DW) followed by soluble phenolic extract and free extract (1.13 ± 0.10 and 0.57 ± 0.06 mg GAE/g DW, respectively). The soluble phenolic fraction has expressed the highest free radical scavenging capacity (76.57± 4.12%) followed by insoluble (69.79± 2.33 %) and free extracts (58.15± 4.44 %). The IC50 values for free, soluble and insoluble bound phenolic were 24.05 ± 3.81, 16.17 ± 1.84 and 18.49 ± 1.92 mg/ml, respectively. Conclusions: The significant differences between all the extracts and antioxidant inhibition in this present study suggested that different forms (free and bound) of extracts did influence the radical scavenging capacity as a whole.
Background: Oral disease in association of pregnancy outcome has been long researched.
Most pregnant women perceived that oral disease in pregnancy are expected and considered
to be normal. Objective: This study aims to evaluate the knowledge of pregnant women and
their practices towards oral disease. Methods: 296 pregnant mothers were recruited from
government clinics in Kuantan, Malaysia. A validated and self -administered questionnaire
assessing knowledge, attitudes and practices towards oral health was used. Results were
analysed by descriptive analysis, chi square test and multiple logistic regression. Results:
Most respondents showed poor knowledge on oral health problem with its pregnancy
outcome (66.6%) and poor attitude about dental health during pregnancy (53.4%). Half of
them had good practice on oral health. Tooth cavity (46.3%) and gum bleeding (29.4%) were
the commonest problem reported by them. Only one third of the mothers utilize dental
service. Higher level of education was associated with better oral health practice [OR:0.02 CI
(1.12,3.92)] Conclusions: Knowledge on the relationship between oral health and pregnancy
outcome is still low among pregnant mothers. Utilization of dental service was also low. High
level of education is proven to give better oral health care.
Introduction: The aim of this study is to determine the satisfaction level of hearing aid users in different types and degrees of hearing loss using the satisfaction with amplification in daily life (SADL) questionnaire. Methods: 35 hearing aid users with different types of hearing loss who sought help from the International Islamic University, Malaysia (IIUM) Hearing and Speech Clinic at Jalan Hospital Campus, Kuantan, IIUM Medical Specialist Centre and private hearing aid centres were involved in this study. The data was collected from the participants who filled in the Malay SADL questionnaires. Results: Among the thirty-five (35) participants, there was no significant difference reported between the types of hearing loss and their satisfaction level in the SADL global score and each of the subscales. It was found that satisfaction level with the hearing aids may depend on several factors such as cosmetic preference, cost of hearing aid and audiologist competence. Meanwhile, in terms of degrees of hearing loss, 80% of the users were relatively satisfied with their hearing aids. Yet, there was no correlation between hearing aid users’ satisfaction level and their degrees of hearing loss for all subscales and SADL global score. Conclusions: This study indicates that although hearing aid users reported to be satisfied with their hearing aids; there are some who are not satisfied in terms of feedback, telephone use, cosmetic appearance and costs of hearing aid. The findings of this study can benefit the audiologists, as they would be able to use the information to help future patients understand and adapt to the use of the hearing aids better.
A guideline on Basic Occupational Health Services (BOHS) has been established jointly by ILO/WHO/ICOH in response to poor achievements of the Occupational Health Services (OHS), especially among workers in small and medium enterprises at the global level. Malaysia. The international guideline describes competent and skilled human resources as an essential strategy for BOHS implementation. This commentary will discuss the challenges faced by current occupational health personnel providing OHS in Malaysia and proposes improvements of human resource development for future BOHS in Malaysia to ensure fair and better OHS coverage for Malaysian workers.
Introduction: Clinacanthus nutans is used as natural nutraceuticals for prevention and treatment of cancer. The purpose of this study is to (i) determine the total phenolic content and antioxidant scavenging capacities of C. nutans in free and bound phenolic acid and (ii) study the relationship between TPC and antioxidant scavenging capacities of C. nutans. Methods: The total phenolic contents were measured using Folin-Ciocalteu assay. Free and bound phenolic were examined by using spectrophotometer while antioxidant capacity were evaluated using DPPH (2, 2-diphenyl-1-picrylhydrazyl) scavenging activity assay. Results: Insoluble phenolic acids showed the highest amount of total phenolic content in C. nutans extracts (6.09+ 0.45 mg gallic acid equivalent (GAE)/ g DW) and exhibited highest antioxidant activity (73.3+0.82 %) as compared to free and soluble phenolic extracts. The IC50 values for free phenolic, soluble bound and insoluble bound phenolic extracts were 0.69+0.02 mg/mL, 0.64+0.04 and 0.60+0.006 mg/mL, respectively. There were positive correlation between insoluble bound phenolic content of C. nutans extracts with antioxidant radical scavenging capacity (R2 = 0.893). Conclusions: These results indicate that different phenolic acid forms affect the total phenolic content and antioxidant properties. Natural compounds such as phenolics from C. nutans could be a good source of antioxidant.
Introduction: Clinical studies have shown that people suffering from tinnitus are at a high risk of developing serious psychological disturbances or serious psychological distress (Erlandsson &
Widen, 2004 in Hiller and Goebel, 1998). Thus the purpose of this study was to determine the
relationship between life-time noise exposure and tinnitus experience among young adults in IIUM Kuantan. Methods: A cross sectional study was used to determine whether there is any association between tinnitus experiences and life-time noise exposure among 11 young adults in IIUM Kuantan from age of 18 to 35 years old who are exposed to the noise. Hearing assessment was done using otoscopy, tympanometry and pure tone audiometry. Participants were asked to fill in a questionnaire on tinnitus experience, and were fitted with a noise dosimeter that measured their noise exposure during waking hours. Values collected from dosimeter were then converted into cumulative life-time noise exposure which refers to the equivalent noise exposure per year (Jokitulppo, Tolvenen & Bjork, 2005). Results: Average cumulative life-time noise exposure of the participants is 72.54 dBA ± 6.9459. Fifty five percent (55%) reported of sometimes having tinnitus. No correlation was found between cumulative life-time noise exposure and tinnitus experience. Conclusion: The cumulative life-time noise exposure among young adults in IIUM Kuantan was found to be lower than the level considered as hazardous. Despite reports of tinnitus experience, there was no evidence that the tinnitus was due to noise exposure.
Introduction: Dietary calcium intake is important in body system regulation. Inadequate intake
among elderly may lead to various health issues such as osteoporosis and hip fracture. In order to counter the problem, this study was carried out to identify dietary calcium intake among elderly in Kuantan, Pahang. Methods: A face to face interviewer-administered session was done individually with seventy-nine (n=79) subjects aged ≥60 years to collect data on sociodemographic background, health status and dietary intake. Diet history method was used to obtain information related to dietary intake and analyzed using Nutritionist Pro Software. P-value was set at p
Introduction: Collagen and gelatin are essential protein in vertebrates and extensively used in various industries. Methods: In this study, acid-solubilized collagen and gelatin were extracted from the scales of three different species of freshwater fish namely Kelah (Tombroides), Tilapia (Oreochromis niloticus) and Snakehead fish (Channidae) and then further quantified using Bradford assay and separated by molecular weight using SDS-PAGE. Results: The extracted collagen in Tilapia fish scale was found to be the highest with 0.018 of protein absorbance among the other three fish; Kelah fish (0.017) and Snakehead fish (0.011). For gelatin, Snakehead fish scales showed the highest amount of total protein concentration followed by Tilapia and Kelah fish with 0.467, 0.144 and 0.037 μg/μL per g, respectively. Based on the SDS-PAGE results, collagen from all the three freshwater fishes were identified as a type 1 (molecular weight approximately from 95 to 130 kDa) collagen. As for gelatin, only gelatin from Snakehead fish scale was identified to be a type 1(molecular weight approximately from 95 to 130 kDa) while the other two freshwater fishes showed no clear band due to high viscosity of the gelatin produced. Conclusion: It can be said that the fishes investigated in this study have a potential to be the alternative source of collagen and gelatin.
Introduction: Various medium and high tube potentials were utilized to conduct chest x-rays. There
are advantages and disadvantages with regards to image quality and radiation dose when using
medium and high kilovoltage (kVp) technique. However, radiographers have misconstrued
understanding pertaining to the choice of tube potential as well as grid usage when performing chest radiography. Methods: The experimental study was conducted using the PBU-50 phantom by exposing it with medium kVp utilizing grid and non-grid as well as high kVp with grid. All images obtained were evaluated using the modified evaluation criteria for PA chest established by the Commission of European Communities, 1996 whilst the dose area product (DAP) was determined using the Dose Area Product (DAP) meter. The value obtained from the DAP meter was converted to entrance surface dose (ESD) usingCALDOSE_X5.0 software and mathematical formula. Results: The Wilcoxon Signed-Rank Test indicated a significant difference in ESD when using medium and high kVp; Z= -2.666, p
Analyses of conventional morphometric, meristic and truss morphometric were performed on two
species of Pangasiid catfish, Pangasius pangasius and P. nasutus. The purpose is to find characters that help in differentiating these two species to avoid confusion among fish farmers. Three morphometric approaches (conventional, meristic and truss morphometric) were employed to identify the morphological differences. Conventional morphometric suggested eye diameter, body width, body depth, dorsal fin base length and barbells as characters that have significant differences (P< 0.05) between the species, hence making them as potential diagnostic markers. Truss morphometric analyses approved that P. nasutus have larger dorsal fin base length as suggested by conventional morphometry data. Meristic analysis showed significant difference (P
Malaysian is one of the highest sugar consumers in the Asia Pacific region. There has been no available report quantifying sugar intake among Malaysian until Malaysian Adult Nutrition Survey
(MANS) 2003 study was done. However, data concerning sugar consumption among university students is scarce. This study was conducted to assess sugar sweetened beverages intake among International Islamic University Malaysia (IIUM) Kuantan students. A total of 42 of IIUM Kuantan students was recruited by convenience sampling method. A questionnaire consisting of 3 days
food record was distributed to all participants as a tool for data collection. Food record was analyzed using the Nutritionist Pro software prior to statistical analysis with SPSS version 12.0. P value was set as p
This paper aimed to describe variation in apical corneal curvature between unilateral primary pterygium and normal adults utilizing simulated-K and corneal irregularity measurement corneal indices. A total of 100 participants comprise 50 unilateral primary pterygium eyes from 50 patients and 50 normal adults were recruited in this study. Diagnosis and classification of primary pterygium were done by a consultant ophthalmologist (KMK). Standard optometric examinations were performed in all participants. Simulated-K (SimK) and corneal irregularity measurement (CIM) was objectively measured using a corneal topographer. Three measurements based on best image quality for SimK and CIM were taken by single operator in a same visit. Difference for both SimK and CIM parameters between primary pterygium and normal groups were determined via independent T-test. Overall mean and standard deviation (n = 120) of SimK and CIM were found higher in primary pterygium group (9.06 ± 4.49 D and 11.48 ± 3.12) compared to normal (1.63 ± 0.67 D and 0.62 ± 0.24) respectively. Independent T-test results showed significance difference in SimK and CIM values between primary pterygium groups and normal (both P< 0.001). Both SimK and CIM corneal indices can be an important tool in describing and predicting changes on the corneal curvature due to pterygium progression. However, it is worth to note that the detectability of changes in anterior corneal curvature is limited to 5 mm of central corneal curvature.
Acute lymphoblastic leukemia (ALL) is the most common leukemia subtypes among paediatrics in Malaysia. Although treatment options are available but some patients remain incurable, some undergo relapse and many experiences adverse effects by the conventional therapies. Thus, we aim to investigate possible treatment alternative by studying the antileukemogenesis properties of concentrated Nypa fruticans sap called nisaan by focusing on adiponectin expression.
Our study model was CCRF-CEM, an acute lymphoblastic leukemia cell lines. The cells were treated with nisaan at a range of concentration and treated for 24, 48 and 72 hours followed by determination of the leukemic cells viability using tryphan blue method. Effective nisaan concentrations that significantly reduced the cells viability were again treated to the cells followed by determination of the cell proliferation using BrdU colorimetric kit and adiponectin level using adiponectin ELISA kit.
The results showed that, increase concentration of nisaan treatment reduced the cells viability and cells proliferation and enhance the adiponectin level in the leukemic cells.
This preliminary data suggest that Nypa fruticans might has the antileukemogenesis effect on acute lymphoblastic cells by regulating the adiponectin expression.
Food insecurity has become one of the concerning issues in public health. The purpose of this study was to investigate household food security status and its relationship with childhood obesity in Kuantan, Pahang. This comparative cross sectional study was conducted in Kuantan, Pahang among 128 mothers aged 18 to 55 years with the children aged 7 and 13 years. Data on food security status was collected using Radimer/Cornell hunger and food insecurity instrument through telephone survey while children's height and weight as well as socio-demographic data were measured and obtained during schools visits. A total of 23% of the respondents were food secure. However, 77% experienced food insecurity where 52% were household food insecure, 9% women were individual food insecure and 16% fell into the child hunger category. Income (p=0.04), income per capita (p=0.033), household size (p=0.032) and area of living (p=0.001) were the significant risk factors for household food insecurity. The prevalence of overweight and obesity among children were 60.6% in food insecure households which was higher compared to food-secure households (38.4%). However, there were no significant association between childhood obesity and food security status. This study demonstrates that the prevalence of food insecurity and childhood obesity in Kuantan, Pahang is a major concern. The results warrant the need
for further investigation to identify complex interaction between food insecurity and
childhood obesity.
X-ray is produced in form of divergent beam. The beam divergence results to blurring effect that influences image diagnosis. Thus, the blurring effect assessment should be enrolled within the quality control (QC) program of an imaging unit.
For centuries, people have been practising phytomedicine in treating ailments or reducing risk of suffering certain diseases. It is considered as a part of an ancient medicine with interest in it becomes rapidly escalating in this modern era. Expansive and prescribed medicine is not the only true path to treat various illnesses. Without disclaiming the modern medicine, herbs can be used as an alternative or a combined therapy with conventional medication. Phytomedicine or ethnomedicine is not a new
field in the world of research. It has been started long ago since the ancient times. As we realized the expensive modern medication is not the only mean to treat illness, interest in the discovery of remedy through natural or conventional products has become more escalating. (Copied from article)
The ideal imaging system that is providing a good quality image of minimal radiation dose. There are many parameters that influenced image quality and radiation dose on clinical radiography. This study has identified some of the problems whereby there are practitioners do not select the proper size of image receptor (IR) and collimation during the examination. The re-usable of the IR and imaging plate also need to be concerned whether multiple exposures may affect the image
quality or not. The purpose of this study is to investigate the effect of different exposure settings; kVp, mAs, collimation field sizes and different IR’ sizes for image quality and radiation dose. Methods: The wall-mounted x-ray machine act as a sources of radiation which exposed the acrylic cylinder that placed over the IR. The examination is repeated with different kVp, mAs, collimation field sizes and IR’s sizes. The source to image distance (SID) is fixed to 100 cm distance and put Nano dot dosimeter similar level with the top of acrylic to measure the dose. The result analysed by using software ImageJ to measure the Contrast to Noise Ratio (CNR). Results: The percentage of CNR1 and CNR2 reduced as the kVp is increased from (CNR1=77.25, CNR2=64.45), (CNR1=73.47, CNR2=61.22) and (CNR1=62.80, CNR2=57.32) for 50 kVp, 75 kVp and 100 kVp respectively and fluctuate when mAs increased. The CNR and entrance skin dose (ESD) shows higher when x-ray beam collimate according to IR’s size. Conclusions: Overall, the manipulative effect of exposure settings on image quality and ESD shows some positive results. The result also shows inconsistent readings in the CNR and ESD. The percentage of CNR decreased when kVp increases and slightly fluctuate when mAs increased. The ESD reading depicts higher when the kVp and mAs increase as well as when x-ray beam collimated according to IR’s sizes.
In ultrasound imaging there is compromise between the penetration of signal at certain depths into the object and image resolution as the ultrasound probe only can transmit single frequency signals in one transmission. Using curvilinear ultrasound probe with 2 to 5 MHz frequency bandwidth, this study investigated the use of multi-frequency imaging to enhance the quality of phantom images.
Methods: Siemen Acuson X150 with curvilinear ultrasound transducer was used to scan the organs of interest (kidney, gallbladder and pancreas) of the ultrasound abdominal phantom. Different images at the different selected frequencies (2.5, 3.6 and 5.0 MHz) were created by fixing the position and the orientation of the transducer in each of the scanning process. Different-frequency images were generated and combined to produce composite (multi-frequency) image. Results: In this study, the quality of the composite image was evaluated based on signal-to noise ratio (SNR) and the obtained results were compared with the single frequency images. Besides, the comparison was also made in terms of overall image quality (noise and sharpness of organ outline) through perceived image quality analysis. Based on calculated SNR, the composite image of the kidney, gallbladder and pancreas recorded higher SNR value as compared to the single frequency images. However, through perceived image quality, most of the observers viewed that the quality of the composite image of the kidney, gallbladder and pancreas is poor as compared to the single frequency image. Conclusions: Image quality of ultrasound imaging is improved by combining multiple ultrasound frequency images into a single composite image. This is achieved as high SNR is obtained in the composite image. However, through perceived image quality, the overall image quality of the composite image was poor.
Carabiner is one of Personal Protective Equipment (PPE), which is used to protect the users from hazards by reducing any chance of serious injury. Thus, it is very important to detect even a small
defect on the component before it becomes worse that could give harm to the users. The aim of this paper is to find out the appropriate imaging technical factors of steel carabiner by using computed radiography (CR). Methods: Radiographic images of carabiner were obtained by manipulating the values of kVp and mAs with respect to contrast and density. A preliminary study was carried out to determine the exposure factor combination in order to produce perceptible visual quality of radiographic images. Positioning techniques applied in this study were whole view (open-gate and close-gate position) and screw view (open-gate and close-gate position). An assessor was invited to evaluate the radiographs by using Image Quality Criteria Scoring (ICS) adapted from European Guidelines on Quality Criteria for Diagnostic Radiographic Images. Results: Findings showed that the optimum values of kVp and mAs in imaging whole view (open-gate and close-gate) carabiner were 133 kVp and 28 mAs while, for screw view (opengate and close-gate) the range of kVp and mAs preferred were 121 kVp to 133 kVp and 28 mAs to 36 mAs respectively. Conclusion: This study has found that the use of medical CR to expose metal steel such as
carabiner is accepted. By manipulating the imaging parameters, CR can produce a good quality image of carabiner.
Breast cancer is commonest disease amongst women throughout the world and the second leading cause of women’s death. Since 2014, it was reported that approximately 5000 women
were diagnosed with breast cancer every year in Malaysia. Adoption of mammography screening
amongst Malaysian women remains under-utilized because it depends on self-initiatives of
individuals. Amongst the perceived barriers are low knowledge, cost, embarrassment and pain which may then give a negative psychological aspect to health behavior actions. The study aims to determine the level of knowledge and perceived barriers pertaining to mammography amongst female lecturers in Kulliyah of Allied Health Sciences (KAHS), International Islamic University Malaysia (IIUM) Kuantan, Pahang. Methods: A survey was carried out on female lecturers aged 35 years and above in KAHS, IIUM Kuantan. A self-administered questionnaire which consists of three sections; demographic factors, knowledge about breast cancer and perceived barriers pertaining to
mammography were distributed to 30 respondents. Data was analyzed using SPSS version 19.0.
Results: The mean age of respondents was 39.9 years old (SD ± 5.15). Majority of respondents possessed good knowledge of breast cancer. The perceived barriers pertaining to mammography amongst respondents were pain and the procedure being expensive. Conclusions: This study found that most female lecturers in KAHS, IIUM Kuantan possessed good knowledge on breast cancer but have fair knowledge pertaining to breast lumps and the best time for breast screening. The perceived barriers amongst respondents were pain and cost of the procedure.