MyMedR

Fulltext Neem (Azadirachta indica): prehistory to contemporary medicinal uses to humankind

Kumar VS, Navaratnam V

Asian Pac J Trop Biomed, 2013 Jul;3(7):505-14.

PMID: 23835719 DOI: 10.1016/S2221-1691(13)60105-7

The divine tree neem (Azadirachta indica) is mainly cultivated in the Indian subcontinent. Neem has been used extensively by humankind to treat various ailments before the availability of written records which recorded the beginning of history. The world health organization estimates that 80% of the population living in the developing countries relies exclusively on traditional medicine for their primary health care. More than half of the world's population still relies entirely on plants for medicines, and plants supply the active ingredients of most traditional medical products. The review shows the neem has been used by humankind to treat various ailments from prehistory to contemporary.

Fulltext Pharmacological screening of methanolic extract of Ixora species

Latha LY, Darah I, Jain K, Sasidharan S

Asian Pac J Trop Biomed, 2012 Feb;2(2):149-51.

PMID: 23569886 DOI: 10.1016/S2221-1691(11)60210-4

OBJECTIVE: To investigate the antimicrobial activity of methanolic extracts of different parts of Ixora species.

METHODS: Antimicrobial activity was carried out using disc diffusion assay against fungi, gram-positive and gram-negative bacteria.

RESULTS: All methanolic extracts of different parts of Ixora species showed a broad-spectrum of antibacterial and antiyeast activities, which inhibited the growth of at least one bacterium or yeast. There was no remarkable difference between different Ixora species observed in this study.

CONCLUSIONS: The significant antimicrobial activity shown by this Ixora species suggests its potential against infections caused by pathogens. The extract may be developed as an antimicrobial agent.

Fulltext Polyketide and benzopyran compounds of an endophytic fungus isolated from Cinnamomum mollissimum: biological activity and structure

Santiago C, Sun L, Munro MH, Santhanam J

Asian Pac J Trop Biomed, 2014 Aug;4(8):627-32.

PMID: 25183332 DOI: 10.12980/APJTB.4.2014APJTB-2014-0030

To study bioactivity and compounds produced by an endophytic Phoma sp. fungus isolated from the medicinal plant Cinnamomum mollissimum.

Fulltext Prevalence of potential drug-drug interactions among internal medicine ward in University of Gondar Teaching Hospital, Ethiopia

Bhagavathula AS, Berhanie A, Tigistu H, Abraham Y, Getachew Y, Khan TM, et al.

Asian Pac J Trop Biomed, 2014 May;4(Suppl 1):S204-8.

PMID: 25183081 DOI: 10.12980/APJTB.4.2014C1172

To determine the prevalence, clinical significance and the associated risk factors of potential drug-drug interactions (DDIs) at internal medicine ward of University of Gondar (UOG) hospital.

Fulltext Residual effects of TMOF-Bti formulations against 1(st) instar Aedes aegypti Linnaeus larvae outside laboratory

Saiful AN, Lau MS, Sulaiman S, Hidayatulfathi O

Asian Pac J Trop Biomed, 2012 Apr;2(4):315-9.

PMID: 23569922 DOI: 10.1016/S2221-1691(12)60031-8

To evaluate the effectiveness and residual effects of trypsin modulating oostatic factor-Bacillus thuringiensis israeliensis (TMOF-Bti) formulations against Aedes aegypti (Ae. aegypti) (L.) larvae at UKM Campus Kuala Lumpur.

Fulltext Review on pharmacological and toxicologyical effects of oleum azadirachti oil

Koriem KM

Asian Pac J Trop Biomed, 2013 Oct;3(10):834-40.

PMID: 24075352 DOI: 10.1016/S2221-1691(13)60165-3

Oleum azadirachti consists of the oil obtained from dried seeds of Azadirachta indica A. Juss. (family: Meliaceae). Local names of Azadirachta indica A. Juss. are Abodua, aforo-oyinbo, anwe egyane, arista, azad dirakht, azadarakht, azedarach and bead tree. Indigenous to India, and widely distributed in South and South-East Asia and cultivated in Africa, the South Pacific Islands, South and Central America and Australia, and in southern Florida and California, United States of America, it is a straight-boled deciduous tree, which is 6-25 m high. Bark is dark-brown, externally fissured with a buff inner surface and fibrous fracture. Leaves alternately arranged, pinnately compound and up to 40 cm long, and composed of 8-18 short-petiolate narrow-ovate, pointed and curved toothed leaflets, 3-10 cm long and 1-4 cm wide arranged in alternate pairs. The major constituents are oxidized tetranortriterpenes including azadirachtin (azadirachtin A), azadiriadione, epoxyazadiradione, azadirone, nimbidin, nimbin, deacetylnimbin, salannin, gedunin, mahmoodin, 17-hydroxydiradione and related derivatives. It is of various medicinal uses, such as a contraceptive for intravaginal use, a mosquito repellent, and treatment of vaginal infections, treatment of gastric ulcers, cardiovascular disease, malaria, rheumatism and skin disorders, external applications for treatment of septic wounds, ulcers and boils, treatment of allergic skin reactions, asthma, bruises, colic, conjunctivitis, dysmenorrhoea, fever, gout, headache, itching due to varicella, kidney stones, leukorrhoea, psoriasis, scabies, sprains and muscular pain, and wounds. It is also used as an emmenagogue, tonic, stomatic and vermicide. In conclusion, the plant oil had antifertility, antihyperglycaemic, anti-inflammatory, antimicrobial, antiviral, antiulcer, estrogenic, immune, contraceptive, antibacterial, insect repellent, and skin treatment effects.

Fulltext Risk factors and outcomes of imipenem-resistant Acinetobacter bloodstream infection in North-Eastern Malaysia

Deris ZZ, Shafei MN, Harun A

Asian Pac J Trop Biomed, 2011 Aug;1(4):313-5.

PMID: 23569782 DOI: 10.1016/S2221-1691(11)60050-6

To determine the risk factors and outcomes of imipenem-resistant Acinetobacter baumannii (IRAB) bloodstream infection (BSI) cases, since there is very little publication on Acinetobacter baumannii infections from Malaysia.

Fulltext Salutary value of haruan, the striped snakehead Channa striatus - a review

Haniffa MA, Sheela PA, Kavitha K, Jais AM

Asian Pac J Trop Biomed, 2014 May;4(Suppl 1):S8-S15.

PMID: 25183152 DOI: 10.12980/APJTB.4.2014C1015

Murrel namely Channa striatus or haruan contains all essential elements to maintain good health and to recover the lost energy after prolonged illness. The fatty acid composition (% of total fatty acid) indicated the abundant presence of C16:0 fatty acid as 30% and the other major fatty acids were C22:6 (15%), C20:4 (19%), C18:1 (12%) and C18:0 (15%). Haruan contains arachidonic acid (C20:4) as 19.0%, a precursor for prostaglandin and thromboxane biosyntheses. Both fatty and amino acids are important components for wound healing processes. Both the fillet and mucus extracts of haruan were found to exhibit a concentration dependent antinociceptive activity. In vitro antioxidant activity was higher in Channa roe protein hydrolysate than in Labeo roe protein hydrolysate in both DPPH radical scavenging and ferric reducing power. Protein content of roe concentrates (RPC) was found to be 90.2% (Channa) and 82.5% (Lates). Water absorption, oil absorption, foam capacity, stability and emulsifying capacity were found to be higher in Channa RPC than in Lates RPC. Characterization of protein hydrolysates from muscle and myofibrillar samples of haruan showed different kinetic and proteolytic activities. The skin extract of haruan influences the serotonergic receptor system thus they can function as an anti-depressant. Thus, haruan is the best example for food as medicine.

Fulltext Subacute oral toxicity study of ethanolic leaves extracts of Strobilanthes crispus in rats

Lim KT, Lim V, Chin JH

Asian Pac J Trop Biomed, 2012 Dec;2(12):948-52.

PMID: 23593574 DOI: 10.1016/S2221-1691(13)60005-2

To examine the oral toxicity of repeated dosing of Strobilanthes crispus (S. crispus) ethanol leaves extract on the liver and kidney functions in Sprague Dawley rats.

Fulltext The biology and demographic parameters of Aedes albopictus in northern peninsular Malaysia

Aida HN, Dieng H, Ahmad AH, Satho T, Nurita AT, Salmah MR, et al.

Asian Pac J Trop Biomed, 2011 Dec;1(6):472-7.

PMID: 23569816 DOI: 10.1016/S2221-1691(11)60103-2

OBJECTIVE: To generate life table characteristics for the dengue vector Aedes albopictus (A. albopictus) under uncontrolled conditions, incorporating both the aquatic and the adult stages.

METHODS: Ten females derived from wild pupae were allowed to fully blood-feed on restrained mice. 774 eggs were hatched in seasoned water. F1 larvae were followed for development until their F2 counterparts emerged as adults. Some population parameters were monitored (F1) or estimated (F2).

RESULTS: A. albopictus exhibited increased fecundity and egg hatch success. Immature development was quick. Immature survival was high, with lowest rate in the pupal stage. Adult emergence was about 81% and sex ratio was close to 1:1. Generational mortality (K) was about 28%. A high proportion of females completed a reproductive cycle and the obtained parity rate was predicted to lead to higher fecundity in the next generation.

CONCLUSIONS: It can be concluded that natural A. albopictus populations in Penang seem largely determined by quick development in combination with low immature loss and increased oviposition.

Fulltext Toxicity effects of water extracts of Holothuria atra Jaeger in mice

Hashim RB, Azizan NA, Zamli Z, Zulkipli FH, Mazlan N, Althunibat OY

Asian Pac J Trop Biomed, 2014 Aug;4(8):614-7.

PMID: 25183330 DOI: 10.12980/APJTB.4.201414B154

To determine lethal median dose (LD50) and histopathological toxicity of water extract of Holothuria atra (H. atra) in mice.

Fulltext Toxicity of cadmium and lead on tropical midge larvae, Chironomus kiiensis Tokunaga and Chironomus javanus Kieffer (Diptera: Chironomidae)

Ebau W, Rawi CS, Din Z, Al-Shami SA

Asian Pac J Trop Biomed, 2012 Aug;2(8):631-4.

PMID: 23569984 DOI: 10.1016/S2221-1691(12)60110-5

To investigate the acute toxicity of cadmium and lead on larvae of two tropical Chironomid species, Chironomus kiiensis (C. kiiensis) Tokunaga and Chironomus javanus (C. javanus) Kieffer.

Fulltext Unusual developing sites of dengue vectors and potential epidemiological implications

Dieng H, Saifur RG, Ahmad AH, Salmah MR, Aziz AT, Satho T, et al.

Asian Pac J Trop Biomed, 2012 Mar;2(3):228-32.

PMID: 23569903 DOI: 10.1016/S2221-1691(12)60047-1

To identify the unusual breeding sites of two dengue vectors, i.e. Aedes albopictus (Ae. albopictus) and Aedes aegypti (Ae. aegypti).

Displaying publications 41 - 53 of 53 in total