Canarium odontophyllum Miq. fruit, popularly recognized as dabai fruit in Sarawak, is a
seasonal fruit found in the tropical rainforest of East Malaysia. A dabai fruit can be divided into
several anatomical parts, and different parts of the fruit have different valuable phytochemicals. Due
to the lack of promotion, dabai fruit is viewed as nutritionally inferior fruit by the public. On the
contrary, the fruit is rich in nutrients such as protein, fat, carbohydrates, sodium, calcium and iron.
Many phytochemicals have been detected from different parts of dabai fruit, and these molecules have
been linked to beneficial properties such as hypolipidemic, anti-atherosclerotic, anti-cholinesterase,
antimicrobial and potentially anti-diabetic. The aim of this article is to review research studies on this
fruit in order to provide adequate baseline information for commercial exploitation as well as for
future studies.
Nitric oxide (NO) is a signaling molecule involved in numerous physiological processes in
both animals and plants. The bioactivity of NO is mainly transduced via post-translational modification
of cysteine residues of proteins termed S-nitrosylation. Interestingly, a number of key regulatory
components in plant defense responses have been found to be regulated by S-nitrosylation making this
type of protein modification an important modulator of plant immunity. As a signaling molecule, NO
intimately interact with other important molecules such as reactive oxygen species. Since the
identification of NO in plants, increasing number of papers isbeing published in the area of NO biology
each year. Here, a collection of papers describing the role of NO in plant immunity has been brought
together to provide a bird's-eye view on the focus area.
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the leading nosocomial
pathogen that is also emerging as a zoonotic pathogen. In this review, it was observed that rapid
emergence of new MRSA clones at a higher frequency has ushered in a new knowledge on the clonality
and epidemic potentials of MRSA. Secondly, the success of treatment and management of MRSA
infection is threatened by the diversity in the clonal types. This is because different clones harbours
different antibiotics resistance characteristics and as such respond differently to treatment. Furthermore,
clonal replacement of hospital-acquired MRSA with community -acquired MRSA has also been
observed. Thirdly, the transmission of MRSA even though previously thought to be exclusively within
the hospital setting through hand contact and nasal colonization has now spread to the community and in
addition human to animal and animal to human transmission has also been observed. Similarly, pet
owners, veterinarians and farmers have been described as high-risked group with potentials of becoming
reservoirs of MRSA. Furthermore, the adoption of hand hygiene in healthcare setting have to a great
extent reduced the incidence of MRSA in the hospital. And lastly, the advent of molecular typing such as
Pulsed Field Gel Electrophoresis (PFGE), Multi Locus Sequence Typing (MLST), Staphylococcal protein
A typing (Spa typing) and Double Locus Sequence Typing (DLST) have proven to be a useful tool in
providing valuable information on the evolution and clonal diversity of MRSA. These in turn help
researchers to answer some pertinent questions on the epidemiology of MRSA.
Burkholderia pseudomallei are Gram negative highly pathogenic bacteria of humans and
animals causing a multisystemic disease called melioidosis. They have recently gained a lot of interest
from the research community and public health organisations because of their great potential to be
used as an agent of bioterrorism. This has made the search for simple, rapid, accurate and the most
definitive means of their detection, identification and discrimination very critical and necessary. This
article aimed to review the molecular techniques used for detection, identification and differentiation
of B. pseudomallei. Although, culture and isolation techniques maintained their usefulness in
confirming cases of melioidosis, their time limitation (can take up to a week for confirming diagnosis)
leads to the search for rapid and simple techniques. Consequently, serology-based tests have been
developed which are both faster and less sophisticated. However, the presence of high background
titre levels and cross-reaction with other organisms make it less reliable. Thus, efforts have been
directed to explore rapid and accurate molecular techniques and resulting in the development and
validation of various PCR-based identification techniques targeting either single or multiple genes.
Although requiring some level of instrumentation and expertise, PCR-based techniques have been
reported to be very useful in diagnosis of melioidosis. We recommend the 16S rRNA PCR (especially
augmented with other molecular methods such as gene sequencing and analysis) and MLST
techniques for timely detection, identification and differentiation of B. pseudomallei for routine
diagnosis and epidemiological studies respectively.
Semiconductor metal oxide (SMO) as a sensing layer for gas detection has been widely used. Many researches have been performed to enhance the sensing performance including its sensitivity, reliability and selectivity. Electrical sensors that use resistivity as an indicator of its sensing are popular and well established. However, the optical based sensor is still much to explore in detecting gas. By integrating it with SMO, the sensor offers good alternative to overcome some drawbacks from electrical sensors.
Remote sensing and geographic information system techniques are significant and popular approaches that have been used in recent years to measure and map urban growth patterns. This paper primarily aims to provide a basis for a literature review of urban growth measurement and mapping by using different methods. For this purpose, the general characteristics of measuring and mapping urban growth patterns are described and classified. The strengths and weaknesses of the various methods have been identified from an analysis and discussion of the characteristics of the techniques. Results of reviews confirm that combining quantitative and qualitative techniques, such as Shannon approach and change detection, to measure and map urban growth patterns will improve understanding of the phenomenon of urban growth. Moreover, using social and economic data such as population and income data will improve understanding of the relationships between causes and effects. The integration of social and economic factors with quantitative and qualitative techniques will contribute to a perfect evaluation of urban growth patterns and land use changes, taking technical, social, economic, spatial, and temporal factors into account.
The overall reproductive process consists of both the human sex organs which include the male and female reproductive system. The ability to produce offsprings that have similar characteristic as their parents is the goal of reproduction. The sexual type of reproduction takes place in human and both male and female reproductive system is required. Male reproductive system is mainly concerned with production of semen (whitish viscous fluid emitted from the male reproductive tract that contains sperm and fluids) and transferring it into the female reproductive tract. In this review, we will discuss the latest findings in the research pertaining the male reproductive system and its contribution towards the research in advancement of reproductive physiology.
Clean water is very important for health and well-being of humans and ecosystem. However, over the year, a billion tons of industrial waste, fertilizers and chemical waste were dumped untreated into water bodies, such as rivers, lake and oceans contributing towards water pollution, then threatening human health and ecosystem. Hence, the need for clean water has urged scientists to research and find solutions for improving water quality. Application of nanoparticles in wastewater treatment improves the environmental quality by elimination of harmful pollutants in wastewater. Magnetite is one of the nanoparticles used in wastewater treatment because of its specific large surface area, high reactivity in adsorption and recoverable from treated water via magnetic separation technology. Preparation method of magnetite nanoparticles is the important key to its adsorption efficiency.
Ki-67 expression is strongly correlated with tumour cell proliferation and growth. It is widely used as a proliferation marker in the routine pathological investigation. The nuclear protein Ki- 67 (pKi67) is recognised prognostic and predictive indicator for the biopsies assessment for cancer patients. Clinically, pKi67 has been revealed to associate with metastasis and the clinical stage of tumours. Furthermore, it has been presented that the expression of Ki-67 is significantly higher in malignant tissues with poorly differentiated tumour cells, as compared with normal tissue. The Ki-67 labelling index plays a vital role as an independent prognostic factor for survival rate, which includes all stages and grade categories. There is an association between the ratios of Ki-67 positive malignant cells and patient survival. This review provides an overview of recent advances in detecting Ki-67 in ovarian carcinoma.
This paper discusses the three most prevalent elements of Islamic art that a r e embedded in modern furniture. This study is isolated from three design thinking approaches. A comparative study has been executed between three most apparent elements of Islamic art, which are arabesque, geometric and calligraphy. Those three types of design are applicable and relevant to modern furniture design nowadays. Therefore, the Islamic model was the paradigm in defining the furniture design character. The unstructured parameter within the appropriate method is a significant way of collecting the findings and usually used in the area of furniture design. The main results of this study are on how Islamic pattern is linked with the artistic design elements. The outcome of this investigation also contributes to a significant tendency in contemporary furniture design thinking solutions. Finally, this paper ends with discussions from three types of design thinking, which is the normative, reflective and hermeneutic design that collaborates with the current modern furniture design.
It is claimed by the media that the expansion of Instant Messaging (IM) in recent years affected the quality of formal writing and there are intrusions into such writings (Grace, Kemp, Martin, & Parrila, 2015). The current study examined six articles published in scientific journals in 2009, 2010, 2012, 2013 and 2015 on textism (e.g. gr8 for “great”) to see if there have been any changes in the results of the studies on the quality of writing under the influence of textism in native and non- native groups during the last 6 years. The population in all three studies has been young adults between 18 to 29 years old, male and female. The studies are done through writing tests in academic institutions and schools. Synchronization of the findings over time is important as it can show that if, with the expansion of social media and increasing number of messaging applications, there has been any significant increase in the textism intrusion or not. The content analysis and statistical comparison are used as the methods to compare the studies’ results and to form an armchair study to validate the effects of the textism on formal writing. Based on the chronological and synthesized results, it was found ultimately that in the native group there is not any significant difference between the results over the synchronized time and the media claims are not true, while the non-native learners of English have shown negative intrusions.
Agriculture is one of the latest industries that uses robotic technologies. Cultivation of crops
with high yield and quality can be enhanced when technological sustenance is involved. Pests are
nuisance and cannot be completely eliminated, but with effective control and management. damages
caused by pests could be minimized below economic threshold. Automation in agriculture is stable and
accurate and is mainly incorporated in mechanized farming system. However its numerous application in
different agricultural practices is not well noticed. Hence this paper attempts to provide profound
awareness on robotic technology in agriculture. Robots could have a specific or multiple functions and,
most commonly, they are made up of five basic components; sensors, effectors, actuators, controller and
arms. Use of automation in weeding, weed mapping, micro spraying, seeding, irrigation and harvesting
are progressions which promote sustainable agriculture and food security. In future, solar robots with
battery inverter may be invented.
This paper explores the construct of motivation from the perspective of the instructional designer or teacher. It describes the motivation to learn in the context of intrinsic motivation, Expectancy-value Theory, Self-efficacy Theory, and Attribution Theory. The ARCS motivational model is examined in detail before discussing how motivation can be integrated in instructional design to enhance learning. This paper also explicates Cheng and Yeh’s (2009) framework in the context of classroom learning.
Serotypes B: 2 and E: 2 of Haemorrhagic septicaemia found in Asia and Africa cause an economically important disease that affects cattle and buffaloes. The disease has a feature of short clinical course and high morbidity and mortality rates. However, animals surviving HS are usually characterized by decrease productivity. There is paucity of knowledge in the involvement of the reproductive system and its organizer hormones in animals afflicted with HS. Therefore, this review aimed to gather information and provide more details on reproductive pathophysiology and its modifications in buffaloes and cattle as a result of P. multocida B: 2 infections.
This review paper discussed about publications related to micropropagation of bamboo species. In recent years, the application of tissue culture technique like in vitro micropropagation has been used to meet the demands for bamboo planting materials. In the past 30 years, protocols for micropropagation of various bamboo species have been established by researchers from all over the world. The controlling factors for cultures such as the explants, culture medium, carbon sources, combination and concentration of plant growth regulators and other additional additives are varied. The controlling factors are crucial in developing successful regeneration protocols for various bamboo species. This paper attempts to review and summarize the available and up-to-date information regarding in vitro micropropagation of bamboos.
Aquaculture, especially shrimp production is the world`s fastest growing food production
industry, due to increased demands for seafood. Conceivably, disease outbreak is the major setback
which brings about high mortality and reduction or loss of production. The conventional use of
antibiotics both prophylactically and therapeutically had recently not only been ineffective but
incriminated, in drug residue which poise danger to consumption by humans. Hence, a better
alternative was importantly required. The use of Immunoprophylaxis has potential of being a safety
measure in the prevention of outbreak of diseases or spread of already established disease in aquatic
invertebrates, where the shrimps and prawns belong. Immunoprophylaxis includes the prevention of
disease by production of passive immunity. The major infectious agents that are responsible for high
morbidity and high mortality in shrimp industry are viruses and bacteria. Others include fungi,
parasites and protozoans but less threatening than the two former. Among the referenced groups of
bacteria in shrimp disease, gram negative bacteria are more virulent. Vibrio, a member of this gram
negative groups has been implicated to be the most causative agent of bacterial infections in shrimps.
This review examined the components of the cell membrane of these bacteria that have been reported
to confer immunity on the host. They include outer membrane proteins, lipopolysaccharide and
peptidoglycan. These components could elicit immune response and confer protection.
The hydrological effects of climate variation and land use conversion can occur at various spatial scales, but the most important sources of these changes are at the regional or watershed scale. In addition, the managerial and technical measures are primarily implemented at local and watershed scales in order to mitigate adverse impacts of human activities on the renewable resources of the watershed. Therefore, quantitative estimation of the possible hydrological consequences of potential land use and climate changes on hydrological regime at watershed scale is of tremendous importance. This paper focuses on the impacts of climate change as well as land use change on the hydrological processes of river basin based on pertinent published literature which were precisely scrutinized. The various causes, forms, and consequences of such impacts were discussed to synthesize the key findings of literature in reputable sources and to identify gaps in the knowledge where further research is required. Results indicate that the watershed-scale studies were found as a gap in tropical regions. Also, these studies are important to facilitate the application of results to real environment. Watershed scale studies are essential to measure the extent of influences made to the hydrological conditions and understanding of causes and effects of climate variation and land use conversion on hydrological cycle and water resources.
The successful in vivo horizontal transfer of mobile genetic elements carrying resistance and virulence determinants have contributed immensely to a global dissemination of virulent and multi-drug resistant pathogens. In addition, the pathogenesis of MRSA infection is enhanced via initial colonization of the skin through the component of the microbial surface antigen recognizing adhesive matrix molecules and by their ability to evade host immune response. Furthermore, it was also observed that the genetic diversity of pathogenic MRSA is due to its’ ability to rapidly acquire resistance and virulence determinants. A characteristic feature that made it one of the most important nosocomial pathogen worldwide. Similarly, the expression of virulence gene in MRSA has been observed to be regulated by the accessory gene regulator system (agr). These system is made up of a series of genes whose product build up quorum-sensing regulatory mechanisms that is growth dependent. In addition, at a certain growth stage, the agr systems triggers a pronounced changes in the expression of genes called the quorum sensing. The findings of this review affirms the importance of horizontal gene transfer in the dissemination of resistance and virulence determinants and as well as the genetic diversity of MRSA.
Facility Layout Problem (FLP) is a NP-hard problem concerned with the arrangement of facilities as to minimize the distance travelled between all pairs of facilities. Many exact and approximate approaches have been proposed with an extensive applicability to deal with this problem. This paper studies the fundamentals of some well-known heuristics and metaheuristics used in solving the FLPs. It is hoped that this paper will trigger researchers for in-depth studies in FLPs looking into more specific interest such as equal or unequal FLPs.
Branching channel flow refers to any side water withdrawals from rivers or main channels.
Branching channels have wide application in many practical projects, such as irrigation and drainage
network systems, water and waste water treatment plants, and many water resources projects. In the
last decades, extensive theoretical and experimental investigations of the branching open channels
have been carried out to understand the characteristics of this branching flow, varying from case
studies to theoretical and experimental investigations. The objectives of this paper are to review and
summarise the relevant literatures regarding branching channel flow. These literatures were reviewed
based on flow characteristics, physical characteristics, and modeling of the branching flow.
Investigations of the flow into branching channel show that the branching discharge depends on many
interlinked parameters. It increases with the decreasing of the main channel flow velocity and Froude
number at the upstream of the branch channel junction. Also it increases with the increasing of the
branch channel bed slope. In subcritical flow, water depth in the branch channel is always lower than
the main channel water depth. The flow diversion to the branch channel leads to an increase of water
depth at the downstream of the main channel. From the review, it is important to highlight that most
of the study concentrated on flow characteristics in a right angle branch channel with a rigid boundary.
Investigations on different branching angles with movable bed have still to be explored.