This article provides data regarding the performance of zinc sulphate as a coagulant for treating rubber industry wastewater. The effect of four factors on removal efficiency of nine parameters is investigated, namely: pH, mixing speed, dosage of coagulant (zinc sulphate) and retention time. Response surface methodology was used to investigate the effect of selected variables. The data obtained from face centered composite design (FCCD) were analyzed by using analysis of variance (ANOVA) and regression model to find the optimum operating conditions for the selected factors.