Studies were conducted to assess the percutaneous absorption of the triacyglycerols (TAGs), tocols and carotenoids present in crude and refined palm oil. In vitro experiments using upright Franz diffusion cells were employed to investigate the permeability of these compounds across full thickness human skin and into the receptor solution. Cetrimide, a cationic surfactant was chosen to be used as a solubilising agent in the receptor phase with an optimum concentration of 3.0 mg/mL and was able to provide sink conditions throughout the permeation. TAGs, tocols and carotenoids all permeated human skin from crude palm oil (CPO), whereas only TAGs permeated when refined palm oil (RPO) was used. Of the TAGs, oleic acid-containing TAGs was preferentially absorbed despite palmitic acid being the most prevalent fatty acid (FA) in TAGs. Tocols in the form of α-T3 showed the highest permeation followed by γ-T3, α-T and the lowest permeation was observed for δ-T3. Carotenoids (α-carotene and β-carotene) also showed an appreciable amount of permeation from CPO.
An exploratory study to ascertain the public’s awareness of community pharmacy
and pharmacists in a selected subset of the Malaysian population was undertaken,
utilising an interviewer-administered structured questionnaire approach. A total
score was computed for each respondent, ranging from a possible minimum of 0 and
a maximum of 24. The scores achieved were arbitrarily categorised into poor (19) levels of general knowledge
regarding community pharmacy and pharmacists. The scores achieved ranged from
3 to 21, with an average “fair” score of 13.7. The results showed that 93.6% of the
respondents (n = 561) interviewed had heard of the term “pharmacist” before.
Interestingly, 17.5% of the respondents were of the opinion that pharmacists
worked on farms. A significant 77.4% perceived that a pharmacist served in a
doctor’s clinic. It was noted that 84.1% of those surveyed would go to doctors for
advice on medicine, while only 49.4% would seek a pharmacist. A majority (76.7%)
of the respondents interviewed chose to go to a doctor’s clinic for a screening test.
The study amplifies the need for a more aggressive projection of the pharmacist’s
image in the community in order to be recognized and accepted by the public as an
integral partner in the health care profession.