MATERIALS AND METHODS: Kepok banana peel was macerated using 70% ethanol. The extract is made in the form of a gel formulation because it has a high water content so it can moisturise the skin and spread easily when applied. This research was conducted with 25 male rats in 5 treatment groups. The gel was given 30 minutes after the rats were induced with 0.1 ml of 1% carrageenan. The rat antiinflammatory test was observed through oedema volume data and the percentage of anti-inflammatory activity. Data analysis used the ANOVA test (p<0.05).
RESULTS: The treatment group had an anti-inflammatory effect which was marked by a significant difference from the negative control group.
CONCLUSION: The effective dose of ethanol extract gel of kepok banana peel as an anti-inflammatory is 8%.