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  1. Ma G, Eng AE, Chiang SK, Hao F, McIntyre RS, Zhou D, et al.
    PMID: 39901842 DOI: 10.1111/pcn.13788
    AIM: Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that may persist into adulthood, with no established objective diagnostic tool yet. This study aims to propose a multimodal objective assessment tool involving clinical assessments, functional neuroimaging, and oculomotricity measurement for ADHD in young adults.

    METHODS: Seventy-one medication-naïve patients and 71 healthy controls (HCs) aged 18 to 28 underwent clinical interviews, Conners' Adult ADHD Rating Scale (CAARS) questionnaire, functional near-infrared spectroscopy (fNIRS), oculomotricity task, and Conners' Continuous Performance Task (CPT) 3rd edition. Student's t-tests with Bonferroni's correction were performed to compare the performance between groups, and logistic regression was used for classification.

    RESULTS: ADHD patients had significantly lower frontal hemodynamic response during verbal fluency task (VFT) (P = 0.0003), more anticipatory eye movements during overlap task (P = 0.0006), higher latency (P 

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