Introduction: Eating seafood has become a major health concern for many people due to the present of heavy met- al especially cadmium (Cd). Cd can accumulate in the body and disrupt the normal cellular processes which will eventually lead to organ damage. This study aims to determine the seafood consumption pattern and blood cadmium (BCd) as well as the association between these two variables among respondents living along the coastal area of Melaka. Methods: Pretested questionnaires were used to collect background and food frequency intake from coastal villagers through convenient sampling method. Venous blood samples were analysed by using Inductively Coupled Plasma Mass Spectrometry (ICP-MS) for BCd determination. Results: A total of 63 respondents who 54% were female with median age of 34 years old provided complete data in this study. The most frequently consumed seafood and its product were shrimp paste (31.5%) followed by mackerel (13.6%), hardtail-scad (6.2%), flatfish (4.5%) and fish ball (4.0). All blood samples showed the present of Cd with median (IQR) = 0.076 (0.1) μg/L and ranged between 0.007 to 1.284 μg/L. The finding showed no association between frequently consumed seafood and low BCd of the respondents. On the other hand, gender was found to be significantly associated with the BCd. Conclusion: Seafood consumption pattern was not significantly associated with BCd which suggests that frequent seafood consumption may not contribute much to BCd level among the respondents as well as it may indicates safe consumption of these seafood available in the study location.
Introduction: Accumulation of heavy metals through seafood consumption constitutes a significant potential threat to human health. Biomonitoring of whole blood heavy metals level gave an insight into the internal body burden to the exposure of heavy metals. The aims of this study were to assess the blood heavy metals (arsenic and lead) level among the coastal community of Melaka and to determine their association with sociodemographic background and potential sources of heavy metals accumulation. Methods: Respondents were recruited through purposive sampling technique based on inclusion and exclusion criteria. The questionnaires were distributed to obtain sociodemograph- ic information, the frequency of seafood intake and smoking habit. Blood samples were obtained on a voluntary basis. A total of 63 respondents completed all the information required. The heavy metals concentration in blood was determined by inductively coupled plasma- mass spectrometry (ICP-MS). Results: The blood arsenic (BAs) con- centration of respondents was 0.076 (0.059 – 0.107) µg/L and the blood lead (BPb) concentration of respondents was 1.204 (0.670 – 2.094) µg/L respectively. A significant association was observed between seafood-based product frequency intake and BPb concentration (p < 0.05). Other seafood frequency intake and background factors were not significantly associated with the BAs and BPb concentration of respondents. Conclusion: The findings showed that arsenic and lead levels in the blood of respondents along the coastal area of Melaka did not exceed the blood heavy metals reference levels and there was also lack of associations between blood heavy metals concentration and the potential factors of heavy metals accumulation studied.