This research demonstrates the application of novel optimization methods in the realm of renewable energy and contributes to the development of environmentally friendly electricity generation and consumption. In this study, an improved version of the Al-Biruni algorithm has been proposed for Hybrid Renewable Energy Systems (HRES) optimization, which includes fuel cells, photovoltaic cells, and windmills. The algorithm considers supply, demand, and energy storage constraints and seeks the best combination of energy sources to meet load demand while reducing total system cost. Inspired by ancient Iranian philosopher Abu Biruni, the proposed method includes modifications to explore solution space efficiently and improve answer value. The proposed HRES model is applied to a case study from Dunhuang City, China, and its findings are validated by comparing it with other optimization approaches. The Modified Al-Biruni Earth Radius (MBER) algorithm is found to be the most efficient and reliable system, costing 4.23 million units of currency. Compared to other optimization approaches, MBER exhibited a total cost of 4.1 million US dollars, 0.009, 3.7, 3.7, LPSP, and 356 h per year. The overall cost is 5.26 million units of currency with a 0.5% Loss of Power Supply Probability (LPSP), which directly impacts system performance and dependability. The improved Al-Biruni algorithm can efficiently optimize the system, reduce costs, and increase load supply, contributing to the growth of renewable energy sources and the application of advanced meta-heuristic techniques in complex energy systems.
Based on the framework theory of industrial digitization, digital industrialization, digital governance and digital value-added in a sustainable environment, this paper systematically studies the relevant elements of governance and value distribution in the sustainable environment of global trade, and its impact on the development path of human beings. This paper explores the way to embed digital technology into the global value chain to realize digital empowerment, measures the competitiveness index of Keqiao's textile industry in the global value chain, analyzes the technical and environmental challenges faced by China's textile industry in the digital age, and proposes the corresponding countermeasures to deal with the impact of global value chain participation and to improve the international competitiveness of China's textile industry.
Nanotitanium dioxide (nTiO2) is widely used as a food additive, leading to chronic dietary exposure and rising health concerns. Although adverse effects on the liver and gut microbiota have been individually investigated, whether gut microbiota mediates nTiO2-induced liver injury remains unclear, especially given the well-established role of the gut-liver axis in hepatic physiology and pathology. Herein, we explored the long-term hepatotoxic effects of oral nTiO2 in mice and the underlying mechanisms through the lens of gut-liver axis crosstalk. Our results showed that chronic exposure to nTiO2 induced dose-dependent liver injury and the disorder of the gut microbiota. Spearman correlation analysis suggested the reduced abundance of beneficial taxa, notably g_Lactobacillus and g_Bacteroides, was strongly associated with elevated intestinal inflammation markers, impaired liver function indicators, and altered hepatic metabolite profiles. Fecal microbiota transplantation demonstrated that nTiO2-perturbed microbiota directly caused liver injury, while colonization with Lactobacillus intestinalis reversed this toxic phenotype, confirming the important role of gut microbiota in the liver injury mediated by nTiO2. More importantly, we found the administration of indole-3-propionic acid (IPA), one of the Lactobacillus-derived indole compounds, restored microbiota homeostasis and alleviated liver toxicity. Mechanistically, IPA increased the expression of MERTK receptor in Kupffer cells, enhancing their phagocytic capacity to redirect nTiO2 accumulation from hepatocytes to Kupffer cells, thereby reducing hepatic oxidative stress and inflammation. Collectively, these findings establish gut microbiota as a critical mediator of nTiO2-induced liver injury, highlight the hepatoprotective role of microbiota-derived IPA, and provide effective strategies for risk intervention against foodborne nanomaterials.
The Qinghai-Tibet Plateau endemic Chinese mountain cat has a controversial taxonomic status, whether it is a true species or a wildcat (Felis silvestris) subspecies and whether it has contributed to cat (F. s. catus) domestication in East Asia. Here, we sampled F. silvestris lineages across China and sequenced 51 nuclear genomes, 55 mitogenomes, and multilocus regions from 270 modern or museum specimens. Genome-wide analyses classified the Chinese mountain cat as a wildcat conspecific F. s. bieti, which was not involved in cat domestication of China, thus supporting a single domestication origin arising from the African wildcat (F. s. lybica). A complex hybridization scenario including ancient introgression from the Asiatic wildcat (F. s. ornata) to F. s. bieti, and contemporary gene flow between F. s. bieti and sympatric domestic cats that are likely recent Plateau arrivals, raises the prospect of disrupted wildcat genetic integrity, an issue with profound conservation implications.
In recent years novel human respiratory disease agents have been described for Southeast Asia and Australia. The causative pathogens were classified as pteropine orthoreoviruses with a strong phylogenetic relationship to orthoreoviruses of bat origin.
The prevalence of dyslipidaemia has been increasing in the Asia-Pacific region and this is attributed to dietary changes and decreasing physical activity. While there has been substantial progress in dyslipidaemia therapy, its management in the region is hindered by limitations in awareness, adherence and healthcare costs. The Asian Pacific Society of Cardiology (APSC) developed these consensus recommendations to address the need for a unified approach to managing dyslipidaemia. These recommendations are intended to guide general cardiologists and internists in the assessment and treatment of dyslipidaemia and are hoped to pave the way for improving screening, early diagnosis and treatment. The APSC expert panel reviewed and appraised the evidence using the Grading of Recommendations Assessment, Development, and Evaluation system. Consensus recommendations were developed, which were then put to an online vote. The resulting consensus recommendations tackle contemporary issues in the management of dyslipidaemia, familial hypercholesterolaemia and lipoprotein(a) in the Asia-Pacific region.