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  1. Herlyani Khosama, Astri Budikayanti, Amy Hui Ping Khor, Lim, Kheng Seang, Ng, Ching-Ching, Indra G. Mansyur, et al.
    Neurology Asia, 2017;22(2):113-116.
    MyJurnal
    Background & Objective: Association between HLA-B*1502 and carbamazepine-induced StevenJohnson
    syndrome/toxic epidermal necrolysis (CBZ-SJS/TEN) was reported in many Southeast Asian
    populations but not in Indonesian. The purpose of this study was to evaluate the association between
    HLA-B*1502 andCBZ-SJS/TEN in an Indonesian population.

    Methods: Patients with history of
    CBZ-SJS/TEN are recruited as cases and those who tolerated CBZ as controls. HLA-B typing was
    performed.

    Results: We recruited 14 cases with CBZ-SJS/TEN and 53 controls. Positive HLA-B*1502
    was found in 8 (57.1%) cases and 14 (26.4%) controls (OR 3.7, 95% CI 1.09-12.61, p=0.035).

    Conclusion: HLA-B*1502 is associated with CBZ-SJS/TEN patients in Indonesian.
  2. Suryani G, Jehosua SY, Herlyani K, Zhi-Jien C, Kheng-Seang L
    Epilepsy Behav, 2021 10;123:108244.
    PMID: 34461382 DOI: 10.1016/j.yebeh.2021.108244
    BACKGROUND: Indonesia is the largest island country in the world with diverse ethnicity and cultural backgrounds. This study aimed to understand the variation in attitudes toward epilepsy among the Javanese, Sundanese, and the Minahasa ethnic groups in Indonesia.

    METHOD: This study recruited Sundanese from Tasikmalaya and Minahasan from Manado using the Indonesian Public Attitudes Toward Epilepsy (PATE) scale. The results were compared to the Javanese and Malaysian data in previous studies.

    RESULT: A total of 200 respondents, 100 from each ethnic group were recruited, with a mean age of 38.51 years. They were predominantly females (54%) and had secondary education level or lower (56.67%). The Javanese had a higher total mean score, indicating poorer attitudes toward epilepsy, as compared to the Minahasan and Sundanese groups. These differences were noted in the personal domain, but not the general domain. There were no significant differences in the mean scores in both personal and general domains between the Minahasan, Sundanese, and Malaysian populations. Subanalysis on the aspects of life showed that the Javanese had a significantly higher score in the aspects of education, marital relationship, and employment.

    CONCLUSION: The attitudes toward epilepsy were similar between the Indonesian (Sundanese and the Minahasan) and Malaysian, except the Javanese with poorer attitude. These differences could be socioeconomically or culturally related.

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