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  1. Longitudinal study on the impact of urinary continence and sexual function on health-related quality of life among Japanese men after robot-assisted radical prostatectomy
    Ngoo KS, Honda M, Kimura Y, Yumioka T, Iwamoto H, Morizane S, et al.
    Int J Med Robot, 2019 Aug;15(4):e2018.
    PMID: 31115140 DOI: 10.1002/rcs.2018
    BACKGROUND: The aim of this study is to investigate the impact of robotic-assisted radical prostatectomy (RARP) on the health-related quality of life (HRQOL).

    METHODS: We prospectively reviewed HRQOL parameters using Short-Form Health Survey, patient self-reporting of urinary incontinence and International Index of Erectile Function, among patients who underwent RARP between 2010 and 2016.

    RESULTS: Among 249 men studied, all had significantly worse HRQOL domain scores at 1 month post operatively but 24 months after surgery, all domains reached or surpassed their baseline values. Only Bodily Pain, General Health, Role-Emotional, Mental Health domains, and Mental Health Composite were significantly improved. Improvement in urinary continence was mirrored by improvements in both Mental and Physical Component Scores.

    CONCLUSIONS: Within a 2-year post-operative period, men who underwent RARP had regained their overall quality of life. The recovery of urinary continence significantly impacted the mental, physical, emotional, and social well-being of those patients.

  2. Statistical optimization of titanium recovery from drinking water treatment residue using response surface methodology
    Krishnan S, Zulkapli NS, Din MFM, Majid ZA, Honda M, Ichikawa Y, et al.
    J Environ Manage, 2020 Feb 01;255:109890.
    PMID: 31790869 DOI: 10.1016/j.jenvman.2019.109890
    Water treatment plants generate vast amounts of sludge and its disposal is one of the most expensive and environmentally problematic challenges worldwide. As sludge from water treatment plants contains a considerable amount of titanium, both can create serious environmental concerns. In this study, the potential to recover titanium from drinking water treatment residue was explored through acid leaching technique. Statistical design for the optimization of titanium recovery was proposed using response surface methodology (RSM) based on a five-level central composite design (CCD). Three independent variables were investigated, namely the acid concentration (3 M-7 M), temperature (40 °C - 80 °C) and solid/liquid ratio (0.005-0.02 g/mL). According to the analysis of variance (ANOVA), the p-value (<0.0001) indicated the designed model was highly significant. Optimization using RSM gave the best fit between validated and predicted data as elucidated by the coefficient of determination with R2 values of 0.9965. However, acid concentration and solid/liquid ratio showed an initial increase in titanium recovery followed by recovery reduction with increasing concentration and ratio. Quadratic RSM predicted the maximum recovery of titanium to be 67.73% at optimal conditions of 5.5 M acid concentration, at a temperature of 62 °C with a solid/liquid ratio of 0.01 g/mL. The verification experiments gave an average of 66.23% recovery of titanium, thus indicating that the successfully developed model to predict the response. This process development has significant importance to reduce the cost of waste disposal, environmental protection, and recovery of economically valuable products.
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