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  1. Jamalluddin NA, Abdullah AZ
    Ultrason Sonochem, 2011 Mar;18(2):669-78.
    PMID: 20933452 DOI: 10.1016/j.ultsonch.2010.09.004
    The development of Fe(III)/TiO(2) catalysts for sonocatalytic degradation of Reactive Blue 4 (RB4) dye in water was carried out using sol-gel method. Their surface morphology, phase transformation and surface characteristics were studied using SEM, XRD and surface analyzer, respectively. Phase transformation from amorphous to anatase occurred at 500°C and transformation of anatase to rutile phase occurred at 700°C. Complete rutile phase was formed at 900°C with corresponding increase in the particle size. Increasing in Fe(III) loading led to a reduction in the anatase phase and with the formation of weaker and broader of diffraction peaks. Surface morphology of the prepared catalyst was clearly observed with increasing calcination temperature. Surface area of the prepared catalyst decreased with increasing calcination temperature or increasing Fe(III) loading. The combination of 0.4 mol% of Fe(III)/TiO(2) with ultrasonic irradiation gave the highest sonocatalytic activity in the removal of RB4 from the aqueous solution. On the other hand, the presence of even small amount of rutile inhibited the catalytic activity of catalyst. 1.5 g/L was the optimum amount of catalyst that led to the highest sonocatalytic degradation of RB4 with an efficiency of 90%. Aeration significantly accelerated the reaction rate. Higher removal at 96% could be achieved with the combination of 0.4Fe(III)/TiO(2) and aeration under ultrasonic irradiation.
  2. Jamalluddin NA, Ismail N, Mutalib SRA, Sikin AM
    Bioresour Bioprocess, 2022 Mar 12;9(1):21.
    PMID: 38647764 DOI: 10.1186/s40643-022-00509-3
    Supercritical carbon dioxide (Sc-CO2) is an alternative tool to extract lipid for the production of fish oil and enzyme from fish by-products (FBPs). In the application of Sc-CO2, this review covers sample preparation, lipid extraction operation, and characterization of fish oil and enzyme as final products. Generally, the fish samples with moisture content less than 20% and particle size less than 5 mm are considered before lipid extraction with Sc-CO2. Sc-CO2 parameters, such as pressure (P), temperature (T), extraction time (text), and flow rate (F), for simultaneous recovery of fish oil, protein, and enzyme were found to be less severe (P: 10.3-25 MPa; T: 25-45 °C, text: 20-150 min; F: 3-50 g/min) than the extraction of fish oil alone (P: 10-40 Mpa; T: 35-80 °C; text: 30-360 min; F: 1-3000 g/min). The enzyme from the Sc-CO2 defatted sample showed higher activity up to 45 U/mg due to lower denaturation of protein as compared to the organic solvent treated sample albeit both samples having similar pH (6-10) and temperature stability (20-60 °C). Overall, mild extraction of lipid from FBPs using Sc-CO2 is effective for the production of enzymes suitable in various industrial applications. Also, fish oil as a result of extraction can be produced as a health product with high polyunsaturated fatty acids (PUFAs) and low contamination of heavy metals.
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