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  1. Muhammad aqil fitri rosli, kamalrul azlan azizan, goh hh
    Sains Malaysiana, 2018;47:3069-3075.
    Nepenthes, locally known as ‘periuk kera’ in Malaysia, is a fascinating species due to uniqueness in their morphology
    in having pitcher organ for carnivorous diet. The pitcher plant has been used for cooking traditional delicacies and
    as traditional remedies to treat illness. Hence, this species might possess beneficial health properties. This study
    aimed to compare the antioxidant activity of the pitcher extracts from Nepenthes ampullaria, Nepenthes rafflesiana
    and their hybrid, Nepenthes × hookeriana. The samples were extracted using methanol:chloroform:water (3:1:1)
    via sonication assisted extraction and the extracts were subjected to three different antioxidant assays, namely
    2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric reducing power (FRAP) and total phenolic content (TPC). Extract from N.
    ampullaria exhibited the strongest radical scavenging activity (0.148 ± 0.04 mg/mL) with the highest ferric reducing
    power (0.009 ± 0.003 mg GA/mg dry weight) among the three species, whereas that of N. rafflesiana possessed the
    highest phenolic content (0.057 ± 0.017 mg GA/mg dry weight). However, the antioxidant capacities of the pitcher
    extracts were not significantly different (p>0.05) between the three species and were much lower than the gallic acid
    as a standard reference.
  2. Lim CK, Nurul Fadhilah Marzuki, Goh YK, You KG, Kah JG, Rafidah Ahmad, et al.
    Sains Malaysiana, 2018;47:3061-3068.
    Basal stem rot disease of oil palm caused by Ganoderma boninense is one of the most devastating diseases in oil palm
    plantation resulting in low yield, loss of palm stands and shorter replanting cycle. To-date, there is no effective treatment
    for Ganoderma infected palms. Control measures, either chemical or cultural approaches, show varying degrees of
    effectiveness. The application of biological control agents which is environmental-friendly could be an attractive solution
    to overcome the problem. Earlier, we had isolated a mycoparasite, Scytalidium parasiticum, from the basidiomata of
    Ganoderma boninense. In vitro assay and nursery experiment showed that this fungus could suppress Ganoderma infection
    and reduce disease severity. However, metabolites which might contribute to the antagonistic or mycoparasitic effect
    remain unknown. In the current study, optimization of fungal sample processing, extraction, and analytical procedures
    were conducted to obtain metabolites from the maize substrate colonized by mycoparasitic ascomycetous Scytalidium
    parasiticum. This technique capable of producing sexual spores in sac-like organs. Untargeted metabolomics profiling
    was carried out by using Liquid Chromatography Time of Flight Mass Spectrometry (LC-ToF-MS). We found that
    S. parasiticum in both liquid- and solid-state cultivation gave higher metabolite when extracted with 60% methanol with
    1% formic acid in combination with homogenisation methods such as ultrasonication and grinding. The findings from
    this study are useful for optimisation of metabolite extraction from other fungi-Ganoderma-plant interactions.
  3. Marhaini Mostapha, Noorhasmiera Abu Jahar, Sarani Zakaria, Sharifah Nabihah Syed Jaafar, Kamalrul Azlan Azizan, Wan Mohd Aizat
    Sains Malaysiana, 2018;47:1259-1268.
    Oil palm is the major crop grown and cultivated in various Asian countries such as Malaysia, Indonesia and Thailand.
    The core of oil palm trunk (COPT) consists of high sugar content, hence suitable for synthesis of fine chemicals and
    biofuels. Increase of sugar content was reported previously during prolonged COPT storage. However, until now, there
    has been no report on protein profiles during storage. Therefore, in this study, protein expression of the COPT during the
    storage period of one to six weeks was investigated using sodium dodecyl sulphate polyacrylamide gel electrophoresis
    (SDS-PAGE) coupled with optical density quantification and multivariate analyses for measuring differentially expressed
    proteins. Accordingly, protein bands were subjected to tryptic digestion followed by tandem mass spectrometry (nanoLCMS/MS)
    protein identification. The results from SDS-PAGE showed consistent protein bands appearing across the biological
    replicates ranging from 10.455 to 202.92 kDa molecular weight (MW) regions. The findings from the principal component
    analysis (PCA) plot illustrated the separation pattern of the proteins at weeks 4 and 5 of storage, which was influenced
    mainly by the molecular weights of 14.283, 25.543, 29.757, 30.549, 31.511, 34.585 and 84.395 kDa, respectively. The
    majority of these proteins are identified as those involved in stress- and defense-related, disease resistance, as well
    as gene/protein expression processes. Indeed, these proteins were mostly upregulated during the later storage period
    suggesting that long-term storage may influence the molecular regulation of COPT sap.
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