MyMedR

Fulltext Impact of COVID-19 on hospitalization of patients with systemic lupus erythematosus (SLE)

Lee WWH, Cheong YK, Teh CL, Wan SA, Chuah SL, Singh BSM

Clin Rheumatol, 2021 11;40(11):4775-4777.

PMID: 34510293 DOI: 10.1007/s10067-021-05920-3

Aseptic meningitis as initial manifestation of systemic lupus erythematosus: Case series

Cheok LH, Lee WWH, Cheng WM, Cheong YK, Teh CL

Lupus, 2022 Feb 08.

PMID: 35132898 DOI: 10.1177/09612033221078213

Aseptic meningitis is a rare presentation of systemic lupus erythematosus (SLE). High index of suspicion is crucial when there is suboptimal response to the initial standard meningitis treatment and presence of connective tissue disease symptoms. We report 3 cases of aseptic meningitis as the main initial presentation of SLE. The diagnosis of SLE as the underlying cause of the aseptic meningitis was supported by the clinical, laboratory and radiological findings. All patients showed good response after treated with immunosuppressant therapy.

Fulltext Systemic Lupus Erythematosus Following COVID-19 Vaccination

Salleh AFM, Teh CL, Akbar SAWM, Cheong YK, Singh BSM, Lee KH, et al.

Eur J Rheumatol, 2022 Oct;9(4):229-230.

PMID: 36476668 DOI: 10.5152/eurjrheum.2022.21120

Gender differences in osteoporotic hip fractures in Sarawak General Hospital

Wan SA, Tiong IK, Chuah SL, Cheong YR, Singh BSM, Lee KH, et al.

Med J Malaysia, 2023 Mar;78(2):207-212.

PMID: 36988532

INTRODUCTION: Osteoporosis and osteoporotic fracture pose a major public health problem in our ageing population, and particularly concerning is the increased morbidity and mortality associated with osteoporotic hip fractures. While overall diagnosis and treatment for osteoporosis have improved, osteoporosis in men remains underdiagnosed and undertreated. We aim to describe the difference in clinical characteristics between elderly men and women with osteoporotic hip fractures in Sarawak General Hospital.

MATERIALS AND METHODS: All patients diagnosed with osteoporotic hip fracture admitted to Sarawak General Hospital from June 2019 to March 2021 were recruited, and demographic data and clinical features were obtained.

RESULTS: There were 140 patients with osteoporotic hip fracture, and 40 were men (28.6%). The mean age for males was 74.1 ± 9.5 years, while the mean age for females was 77.4 ± 9.1 years (p=0.06). The types of fracture consisted of neck of femur=78, intertrochanteric=61 and subtrochanteric=1. More men were active smokers (15% vs 1%, p<0.001). There were 20 men with secondary osteoporosis (50%), while 13 women (13%) had secondary osteoporosis (p<0.001). The causes of secondary osteoporosis among the men were hypogonadism, COPD, glucocorticoid-induced osteoporosis, renal disease, androgen deprivation therapy, thyroid disorder, prostate cancer and previous gastrectomy. There were two deaths among the men and four deaths among the women during the inpatient and 3 months follow-up period. There was no statistical significance between the mortality rates between male patients (5%) and female patients (4%) (p=0.55).

CONCLUSION: There were more females with osteoporotic hip fractures, and there were significantly more males with secondary osteoporotic hip fractures.

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