Background and Aim: Obesity exhibits wide variety of electrocardiogram (ECG) abnormalities in adults. Previous researches have found different results since they tested mostly on children, adolescents, and middle aged persons. However, there’s no clear evidence of the association between obesity and ECG variables, especially in young adults. Hence, the aim of this research is to compare ECG parameters (PR interval, QRS interval, corrected QT, axis and height of P and R wave) of obese with normal BMI young adults.
Materials and method: A cross-sectional observational study was done on 38 students of a private university in Shah Alam. They were aged between 20 to 30 years, involving normal and obese persons. Anthropometric data, arterial blood pressure and standard 12-lead ECGs were collected for every participant. Independent-sample t-tests and non-parametric Mann-Whitney test were conducted to compare data of normal persons and obese persons. Pearson correlation was done to correlate ECG parameters with BMI, Weight and systolic arterial blood pressure.
Results: Heart rate, PR interval, QRS interval and QT interval of obese person were not significantly different from normal. Height of R wave in obese person is more than that of normal person (P
Background and Aims: In every disease, there will be the triggers on the occurrences. One of them is the oxidative stress, an imbalance between free radicals such as reactive oxygen species (ROS) and the antioxidants. The human body manages free radicals through neutralization by the antioxidative defense mechanism, however, when excessive free radicals being produced, it will become less effective. Over 40 years of age, oxidative stress become prominent and may associated with many diseases such as neural disorders and cardiovascular diseases. Oxidative stress can cause damage to lipids, known as lipid peroxidation, producing malondialdehyde (MDA), a marker to detect the degree of oxidative stress. Availability of oxygen (O2) is the main factor of the ROS formation, which could be indicated by haemoglobin (Hb) concentration. Thus, this research is conducted to find out the correlation between Hb concentration and MDA level in healthy middle age adults.
Methods: A correlation study was conducted in a private University, Shah Alam from January 2018 until March 2018. Total 16 participants, who are MSU staffs, age between 45 and 65, with no known diseases, are selected after the consents are gained. Pearson correlation was used for statistical analysis of the data.
Results: It is found that there is a strong correlation between Hb concentration and MDA level (r: .756, p