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  1. Nazirah R, Zuhailawati H, Siti Nur Hazwani MR, Abdullah TK, Azzura I, Dhindaw BK
    Materials (Basel), 2021 Oct 20;14(21).
    PMID: 34771772 DOI: 10.3390/ma14216246
    Considering the necessity for a biodegradable implant alloy with good biocompatibility and mechanical strength, dual ceramic particles of HAP and Al2O3 were added to Mg-Zn alloy to produce a new hybrid composite using powder metallurgy. The paper reports the mechanical and corrosion behaviour of Mg-Zn/HAP/Al2O3 hybrid composites containing variable wt.% HAP and Al2O3 with 15 wt.% total ceramic content. The powders of Mg, Zn, Al2O3 and HAP were milled in a high-energy ball mill, and then compacted under 400 MPa and sintered at 300 °C. Density and compression strength increased with increasing Al2O3 content. HAP facilitated weight gain in Hanks balanced salt solution due to deposition of an apatite layer which promoted anodic behaviour with higher corrosion resistance. A hybrid composite of Mg alloy with 5 wt.% Al2O3 and 10 wt.% HAP displayed 153 MPa compressive strength, 1.37 mm/year corrosion resistance and bioactivity with a CA:P ratio of 1:1.55 and appears to be the most promising biodegradable implant material tested.
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