This paper investigates the issue of fault-tolerant and anti-disturbance attenuation for a two-dimensional modified repetitive control system (2D MRCS) which is described by switched fuzzy systems with multiple disturbances. In particular, the multiple disturbances contain an exogenous disturbance and standard Wiener noise. Specifically, a generalized extended state observer (GESO) is incorporated with the 2D MRCS to estimate both fault and exogenous multiple disturbances so that the disturbances and faults can be attenuated in the control input. Further, the improved 2D MRCS relaxes the stability condition and provides an enhanced tracking performance. Based on the Lyapunov function approach, pole placement technique and average dwell time approach, the stability criteria for the considered system is developed in terms of linear matrix inequality (LMI). Then an algorithm for designing a GESO-based 2D MRC design is developed based on the obtained LMIs. Further, the results developed are validated in the simulation section through three numerical examples.
This study determines the optimal cut-off scores for the Montreal Cognitive Assessment (MoCA) to detect HIV-associated neurocognitive disorders (HAND) in a multi-ethnic Malaysian HIV-positive cohort by developing demographically corrected normative standards among 283 HIV-negative community-based controls with overlapping demographic characteristics. The norms (corrected for age, sex, education, ethnicity) were applied to 342 HIV-positive virally suppressed individuals on cART. Impairment rates were classified using the Global Deficit Score (GDS ≥ .5) method. The MoCA was also scored according to the recommended cut-off of ≤ 26, and functional decline was applied to both impairment definitions to classify HAND per the Frascati criteria. The ≤ 26 cut-off considerably overestimated cognitive impairment in both samples (59.4% HIV-negative; 69.3% HIV-positive). In contrast, corrected scores yielded impairment rates consistent with what has been reported internationally in virally suppressed cohorts (23.4% with 83.3% mild impairment, 16.7% moderate impairment). A supplemental file allowing the computation of corrected MoCA scores and impairment status is included.